Shefrin S - Search Results

1

Comparative computational and experimental analyses of some natural small molecules to restore transcriptional activation function of p53 in cancer cells harbouring wild type and p53^Ser46 mutant.

Shefrin S, Sari AN, Kumar V, Zhang H, Meidinna HN, Kaul SC, Wadhwa R, Sundar D. Shefrin S, et al. Curr Res Struct Biol. 2022 Sep 13;4:320-331. doi: 10.1016/j.crstbi.2022.09.002. eCollection 2022. Curr Res Struct Biol. 2022. PMID: 36164647 Free PMC article.

2

Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action.

Sari AN, Bhargava P, Dhanjal JK, Putri JF, Radhakrishnan N, Shefrin S, Ishida Y, Terao K, Sundar D, Kaul SC, Wadhwa R. Sari AN, et al. Among authors: shefrin s. Cancers (Basel). 2020 May 5;12(5):1160. doi: 10.3390/cancers12051160. Cancers (Basel). 2020. PMID: 32380701 Free PMC article.

3

Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1.

Meidinna HN, Shefrin S, Sari AN, Zhang H, Dhanjal JK, Kaul SC, Sundar D, Wadhwa R. Meidinna HN, et al. Among authors: shefrin s. Front Cell Dev Biol. 2022 Sep 12;10:918970. doi: 10.3389/fcell.2022.918970. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36172283 Free PMC article.

4

Cucurbitacin-B inhibits cancer cell migration by targeting mortalin and HDM2: computational and in vitro experimental evidence.

Huifu H, Shefrin S, Yang S, Zhang Z, Kaul SC, Sundar D, Wadhwa R. Huifu H, et al. Among authors: shefrin s. J Biomol Struct Dyn. 2024 Mar;42(5):2643-2652. doi: 10.1080/07391102.2023.2206914. Epub 2023 May 2. J Biomol Struct Dyn. 2024. PMID: 37129211

5

Construction and characterization of a temperature-sensitive pRC4 replicon for Rhodococcus and Gordonia.

Deedwania A, Karmakar S, Kumar V, Shefrin S, Sundar D, Srivastava P. Deedwania A, et al. Among authors: shefrin s. Gene. 2024 Feb 20;896:147990. doi: 10.1016/j.gene.2023.147990. Epub 2023 Nov 15. Gene. 2024. PMID: 37977321

6

Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody.

Kumar V, Shefrin S, Sundar D. Kumar V, et al. Among authors: shefrin s. J Struct Biol. 2024 Jun;216(2):108087. doi: 10.1016/j.jsb.2024.108087. Epub 2024 Mar 16. J Struct Biol. 2024. PMID: 38494148 Free article.

7

Molecular Insights into the Anticancer Activity of Withaferin-A: The Inhibition of Survivin Signaling.

Wadhwa R, Wang J, Shefrin S, Zhang H, Sundar D, Kaul SC. Wadhwa R, et al. Among authors: shefrin s. Cancers (Basel). 2024 Sep 5;16(17):3090. doi: 10.3390/cancers16173090. Cancers (Basel). 2024. PMID: 39272948 Free PMC article.

8

Synthetic and Natural Inhibitors of Mortalin for Cancer Therapy.

Kaushal S, Gupta S, Shefrin S, Vora DS, Kaul SC, Sundar D, Wadhwa R, Dhanjal JK. Kaushal S, et al. Among authors: shefrin s. Cancers (Basel). 2024 Oct 13;16(20):3470. doi: 10.3390/cancers16203470. Cancers (Basel). 2024. PMID: 39456564 Free PMC article. Review.

9

Sustained release timolol maleate loaded ocusert based on biopolymer composite.

Nair RV, S S, Suresh A, K R A, Nair SC. Nair RV, et al. Among authors: s s. Int J Biol Macromol. 2018 Apr 15;110:308-317. doi: 10.1016/j.ijbiomac.2018.01.029. Epub 2018 Jan 16. Int J Biol Macromol. 2018. PMID: 29341922

10

Therapeutic advances in idiopathic Parkinsonism.

Shefrin SL. Shefrin SL. Expert Opin Investig Drugs. 1999 Oct;8(10):1565-1588. doi: 10.1517/13543784.8.10.1565. Expert Opin Investig Drugs. 1999. PMID: 11139811

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