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Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Caporarello N, Lee J, Pham TX, Jones DL, Guan J, Link PA, Meridew JA, Marden G, Yamashita T, Osborne CA, Bhagwate AV, Huang SK, Nicosia RF, Tschumperlin DJ, Trojanowska M, Ligresti G. Caporarello N, et al. Nat Commun. 2022 Jul 25;13(1):4170. doi: 10.1038/s41467-022-31890-4. Nat Commun. 2022. PMID: 35879310 Free PMC article.
Vascular dysfunction in aged mice contributes to persistent lung fibrosis.
Caporarello N, Meridew JA, Aravamudhan A, Jones DL, Austin SA, Pham TX, Haak AJ, Moo Choi K, Tan Q, Haresi A, Huang SK, Katusic ZS, Tschumperlin DJ, Ligresti G. Caporarello N, et al. Aging Cell. 2020 Aug;19(8):e13196. doi: 10.1111/acel.13196. Epub 2020 Jul 21. Aging Cell. 2020. PMID: 32691484 Free PMC article.
Spontaneous Lung Fibrosis Resolution Reveals Novel Antifibrotic Regulators.
Tan Q, Link PA, Meridew JA, Pham TX, Caporarello N, Ligresti G, Tschumperlin DJ. Tan Q, et al. Among authors: caporarello n. Am J Respir Cell Mol Biol. 2021 Apr;64(4):453-464. doi: 10.1165/rcmb.2020-0396OC. Am J Respir Cell Mol Biol. 2021. PMID: 33493091 Free PMC article.
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation.
Aravamudhan A, Haak AJ, Choi KM, Meridew JA, Caporarello N, Jones DL, Tan Q, Ligresti G, Tschumperlin DJ. Aravamudhan A, et al. Among authors: caporarello n. Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L852-L863. doi: 10.1152/ajplung.00324.2019. Epub 2020 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32159970 Free PMC article.
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation.
Jones DL, Meridew JA, Link PA, Ducharme MT, Lydon KL, Choi KM, Caporarello N, Tan Q, Diaz Espinosa AM, Xiong Y, Lee JH, Ye Z, Yan H, Ordog T, Ligresti G, Varelas X, Tschumperlin DJ. Jones DL, et al. Among authors: caporarello n. J Cell Biol. 2021 May 3;220(5):e202007152. doi: 10.1083/jcb.202007152. J Cell Biol. 2021. PMID: 33625469 Free PMC article.
42 results