Schaefer KG - Search Results

1

The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells.

Russell CM, Schaefer KG, Dixson A, Gray ALH, Pyron RJ, Alves DS, Moore N, Conley EA, Schuck RJ, White TA, Do TD, King GM, Barrera FN. Russell CM, et al. Among authors: schaefer kg. Elife. 2022 Sep 29;11:e75490. doi: 10.7554/eLife.75490. Elife. 2022. PMID: 36173096 Free PMC article.

2

The effects of anthracycline drugs on the conformational distribution of mouse P-glycoprotein explains their transport rate differences.

Nguyen PH, Sigdel KP, Schaefer KG, Mensah GAK, King GM, Roberts AG. Nguyen PH, et al. Among authors: schaefer kg. Biochem Pharmacol. 2020 Apr;174:113813. doi: 10.1016/j.bcp.2020.113813. Epub 2020 Jan 16. Biochem Pharmacol. 2020. PMID: 31954717 Free PMC article.

3

Atomic force microscopy for quantitative understanding of peptide-induced lipid bilayer remodeling.

Schaefer KG, Pittman AE, Barrera FN, King GM. Schaefer KG, et al. Methods. 2022 Jan;197:20-29. doi: 10.1016/j.ymeth.2020.10.014. Epub 2020 Oct 24. Methods. 2022. PMID: 33164792

4

Atomic Force Microscopy Reveals Membrane Protein Activity at the Single Molecule Level.

Chattrakun K, Schaefer KG, Chandler LS, Marsh BP, King GM. Chattrakun K, et al. Among authors: schaefer kg. Methods Mol Biol. 2021;2302:81-99. doi: 10.1007/978-1-0716-1394-8_6. Methods Mol Biol. 2021. PMID: 33877624

5

Controllable membrane remodeling by a modified fragment of the apoptotic protein Bax.

Schaefer KG, Grau B, Moore N, Mingarro I, King GM, Barrera FN. Schaefer KG, et al. Faraday Discuss. 2021 Dec 24;232(0):114-130. doi: 10.1039/d0fd00070a. Faraday Discuss. 2021. PMID: 34549736 Free PMC article.

6

Advantages and potential limitations of applying AFM kymograph analysis to pharmaceutically relevant membrane proteins in lipid bilayers.

Schaefer KG, Roberts AG, King GM. Schaefer KG, et al. Sci Rep. 2023 Jul 15;13(1):11427. doi: 10.1038/s41598-023-37910-7. Sci Rep. 2023. PMID: 37454132 Free PMC article.

7

Drug-Induced Conformational Dynamics of P-Glycoprotein Underlies the Transport of Camptothecin Analogs.

Mensah GAK, Schaefer KG, Bartlett MG, Roberts AG, King GM. Mensah GAK, et al. Among authors: schaefer kg. Int J Mol Sci. 2023 Nov 7;24(22):16058. doi: 10.3390/ijms242216058. Int J Mol Sci. 2023. PMID: 38003248 Free PMC article.

8

Atomic force microscope kymograph analysis: A case study of two membrane proteins.

Weaver DR, Schaefer KG, King GM. Weaver DR, et al. Among authors: schaefer kg. Methods. 2024 Mar;223:83-94. doi: 10.1016/j.ymeth.2024.01.013. Epub 2024 Jan 28. Methods. 2024. PMID: 38286332

9

Probing the Mechanisms Underlying the Transport of the Vinca Alkaloids by P-glycoprotein.

Mensah GAK, Schaefer KG, Roberts AG, King GM, Bartlett MG. Mensah GAK, et al. Among authors: schaefer kg. J Pharm Sci. 2024 Jul;113(7):1960-1974. doi: 10.1016/j.xphs.2024.03.014. Epub 2024 Mar 23. J Pharm Sci. 2024. PMID: 38527618

10

Polymerization mechanism of the Candida albicans virulence factor candidalysin.

Schaefer KG, Russell CM, Pyron RJ, Conley EA, Barrera FN, King GM. Schaefer KG, et al. J Biol Chem. 2024 Jun;300(6):107370. doi: 10.1016/j.jbc.2024.107370. Epub 2024 May 13. J Biol Chem. 2024. PMID: 38750794 Free PMC article.

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