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High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity.
Immunity. 2022 Oct 11;55(10):1953-1966.e10. doi: 10.1016/j.immuni.2022.09.004. Epub 2022 Sep 28.
Immunity. 2022.
PMID: 36174557
Free article.
Leveraging Single-Cell Sequencing for Chimeric Antigen Receptor T Cell Therapies.
Castellanos-Rueda R, Di Roberto RB, Schlatter FS, Reddy ST.
Castellanos-Rueda R, et al. Among authors: schlatter fs.
Trends Biotechnol. 2021 Dec;39(12):1308-1320. doi: 10.1016/j.tibtech.2021.03.005. Epub 2021 Apr 5.
Trends Biotechnol. 2021.
PMID: 33832782
Review.
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speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing.
Castellanos-Rueda R, Di Roberto RB, Bieberich F, Schlatter FS, Palianina D, Nguyen OTP, Kapetanovic E, Läubli H, Hierlemann A, Khanna N, Reddy ST.
Castellanos-Rueda R, et al. Among authors: schlatter fs.
Nat Commun. 2022 Nov 2;13(1):6555. doi: 10.1038/s41467-022-34141-8.
Nat Commun. 2022.
PMID: 36323661
Free PMC article.
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A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications.
Palianina D, Di Roberto RB, Castellanos-Rueda R, Schlatter F, Reddy ST, Khanna N.
Palianina D, et al.
Mol Ther Methods Clin Dev. 2023 Jun 19;30:147-160. doi: 10.1016/j.omtm.2023.06.007. eCollection 2023 Sep 14.
Mol Ther Methods Clin Dev. 2023.
PMID: 37448595
Free PMC article.
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