Brown MC - Search Results

1

Multimodality analysis confers a prognostic benefit of a T-cell infiltrated tumor microenvironment and peripheral immune status in patients with melanoma.

Beasley GM, Brown MC, Farrow NE, Landa K, Al-Rohil RN, Selim MA, Therien AD, Jung SH, Gao J, Boczkowski D, Holl EK, Salama AKS, Bigner DD, Gromeier M, Nair SK. Beasley GM, et al. Among authors: brown mc. J Immunother Cancer. 2022 Sep;10(9):e005052. doi: 10.1136/jitc-2022-005052. J Immunother Cancer. 2022. PMID: 36175036 Free PMC article. Clinical Trial.

2

Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.

Dobrikov MI, Shveygert M, Brown MC, Gromeier M. Dobrikov MI, et al. Among authors: brown mc. Mol Cell Biol. 2014 Feb;34(3):439-51. doi: 10.1128/MCB.01046-13. Epub 2013 Nov 18. Mol Cell Biol. 2014. PMID: 24248602 Free PMC article.

3

Oncolytic polio virotherapy of cancer.

Brown MC, Dobrikova EY, Dobrikov MI, Walton RW, Gemberling SL, Nair SK, Desjardins A, Sampson JH, Friedman HS, Friedman AH, Tyler DS, Bigner DD, Gromeier M. Brown MC, et al. Cancer. 2014 Nov 1;120(21):3277-86. doi: 10.1002/cncr.28862. Epub 2014 Jun 17. Cancer. 2014. PMID: 24939611 Free PMC article. Review.

4

Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysis.

Brown MC, Dobrikov MI, Gromeier M. Brown MC, et al. J Virol. 2014 Nov;88(22):13149-60. doi: 10.1128/JVI.01884-14. Epub 2014 Sep 3. J Virol. 2014. PMID: 25187540 Free PMC article.

5

Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.

Brown MC, Bryant JD, Dobrikova EY, Shveygert M, Bradrick SS, Chandramohan V, Bigner DD, Gromeier M. Brown MC, et al. J Virol. 2014 Nov;88(22):13135-48. doi: 10.1128/JVI.01883-14. Epub 2014 Sep 3. J Virol. 2014. PMID: 25187541 Free PMC article.

6

Cytotoxic and immunogenic mechanisms of recombinant oncolytic poliovirus.

Brown MC, Gromeier M. Brown MC, et al. Curr Opin Virol. 2015 Aug;13:81-5. doi: 10.1016/j.coviro.2015.05.007. Epub 2015 Jun 12. Curr Opin Virol. 2015. PMID: 26083317 Free PMC article. Review.

7

Oncolytic immunotherapy through tumor-specific translation and cytotoxicity of poliovirus.

Brown MC, Gromeier M. Brown MC, et al. Discov Med. 2015 May;19(106):359-65. Discov Med. 2015. PMID: 26105699 Free PMC article. Review.

8

Recombinant oncolytic poliovirus, PVSRIPO, has potent cytotoxic and innate inflammatory effects, mediating therapy in human breast and prostate cancer xenograft models.

Holl EK, Brown MC, Boczkowski D, McNamara MA, George DJ, Bigner DD, Gromeier M, Nair SK. Holl EK, et al. Among authors: brown mc. Oncotarget. 2016 Nov 29;7(48):79828-79841. doi: 10.18632/oncotarget.12975. Oncotarget. 2016. PMID: 27806313 Free PMC article.

9

MNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1.

Brown MC, Gromeier M. Brown MC, et al. Cell Rep. 2017 Feb 7;18(6):1444-1457. doi: 10.1016/j.celrep.2017.01.023. Cell Rep. 2017. PMID: 28178522 Free PMC article.

10

MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.

Brown MC, Gromeier M. Brown MC, et al. Mol Cell Oncol. 2017 Mar 17;4(3):e1306010. doi: 10.1080/23723556.2017.1306010. eCollection 2017. Mol Cell Oncol. 2017. PMID: 28616583 Free PMC article.

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