Kelly JW - Search Results

1

Tafamidis polyneuropathy amelioration requires modest increases in transthyretin stability even though increases in plasma native TTR and decreases in non-native TTR do not predict response.

Monteiro C, Mesgarzadeh JS, Anselmo J, Fernandes J, Novais M, Rodrigues C, Powers DL, Powers ET, Coelho T, Kelly JW. Monteiro C, et al. Among authors: kelly jw. Amyloid. 2023 Mar;30(1):81-95. doi: 10.1080/13506129.2022.2126308. Epub 2022 Sep 30. Amyloid. 2023. PMID: 36178172 Free PMC article.

2

Medium-dependent self-assembly of an amphiphilic peptide: direct observation of peptide phase domains at the air-water interface.

Powers ET, Kelly JW. Powers ET, et al. Among authors: kelly jw. J Am Chem Soc. 2001 Jan 31;123(4):775-6. doi: 10.1021/ja005528i. J Am Chem Soc. 2001. PMID: 11456608 No abstract available.

3

Incorporating beta-turns and a turn mimetic out of context in loop 1 of the WW domain affords cooperatively folded beta-sheets.

Kaul R, Angeles AR, Jäger M, Powers ET, Kelly JW. Kaul R, et al. Among authors: kelly jw. J Am Chem Soc. 2001 Jun 6;123(22):5206-12. doi: 10.1021/ja0102890. J Am Chem Soc. 2001. PMID: 11457382

4

Synthesis, structure, and activity of diclofenac analogues as transthyretin amyloid fibril formation inhibitors.

Oza VB, Smith C, Raman P, Koepf EK, Lashuel HA, Petrassi HM, Chiang KP, Powers ET, Sachettinni J, Kelly JW. Oza VB, et al. Among authors: kelly jw. J Med Chem. 2002 Jan 17;45(2):321-32. doi: 10.1021/jm010257n. J Med Chem. 2002. PMID: 11784137

5

Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity.

Hammarström P, Jiang X, Hurshman AR, Powers ET, Kelly JW. Hammarström P, et al. Among authors: kelly jw. Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16427-32. doi: 10.1073/pnas.202495199. Epub 2002 Sep 25. Proc Natl Acad Sci U S A. 2002. PMID: 12351683 Free PMC article.

6

Ordered Langmuir-Blodgett films of amphiphilic beta-hairpin peptides imaged by atomic force microscopy.

Powers ET, Yang SI, Lieber CM, Kelly JW. Powers ET, et al. Among authors: kelly jw. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):127-30. doi: 10.1002/1521-3773(20020104)41:1<127::aid-anie127>3.0.co;2-f. Angew Chem Int Ed Engl. 2002. PMID: 12491460 No abstract available.

7

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

Hammarström P, Wiseman RL, Powers ET, Kelly JW. Hammarström P, et al. Among authors: kelly jw. Science. 2003 Jan 31;299(5607):713-6. doi: 10.1126/science.1079589. Science. 2003. PMID: 12560553

8

Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action.

Razavi H, Palaninathan SK, Powers ET, Wiseman RL, Purkey HE, Mohamedmohaideen NN, Deechongkit S, Chiang KP, Dendle MT, Sacchettini JC, Kelly JW. Razavi H, et al. Among authors: kelly jw. Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2758-61. doi: 10.1002/anie.200351179. Angew Chem Int Ed Engl. 2003. PMID: 12820260 No abstract available.

9

ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization.

DiDonato M, Craig L, Huff ME, Thayer MM, Cardoso RM, Kassmann CJ, Lo TP, Bruns CK, Powers ET, Kelly JW, Getzoff ED, Tainer JA. DiDonato M, et al. Among authors: kelly jw. J Mol Biol. 2003 Sep 19;332(3):601-15. doi: 10.1016/s0022-2836(03)00889-1. J Mol Biol. 2003. PMID: 12963370

10

Metabolite-initiated protein misfolding may trigger Alzheimer's disease.

Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P Jr, Lerner RA, Kelly JW. Zhang Q, et al. Among authors: kelly jw. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4752-7. doi: 10.1073/pnas.0400924101. Epub 2004 Mar 19. Proc Natl Acad Sci U S A. 2004. PMID: 15034169 Free PMC article.

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