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Clinical Pattern of Tolvaptan-Associated Liver Injury in Trial Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD): An Analysis of Pivotal Clinical Trials.
Alpers DH, Lewis JH, Hunt CM, Freston JW, Torres VE, Li H, Wang W, Hoke ME, Roth SE, Westcott-Baker L, Estilo A. Alpers DH, et al. Among authors: hunt cm. Am J Kidney Dis. 2023 Mar;81(3):281-293.e1. doi: 10.1053/j.ajkd.2022.08.012. Epub 2022 Sep 30. Am J Kidney Dis. 2023. PMID: 36191725 Free article.
Monitoring liver safety in drug development: the GSK experience.
Hunt CM, Papay JI, Edwards RI, Theodore D, Alpers DH, Dollery C, Debruin TW, Adkison KK, Stirnadel HA, Gibbs TG. Hunt CM, et al. Regul Toxicol Pharmacol. 2007 Nov;49(2):90-100. doi: 10.1016/j.yrtph.2007.06.002. Epub 2007 Jun 21. Regul Toxicol Pharmacol. 2007. PMID: 17655994
Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration.
Suzuki A, Tillmann H, Williams J, Hauser RG, Frund J, Suzuki M, Prior F, Aithal GP, Lucena MI, Andrade RJ, Tong W, Hunt CM. Suzuki A, et al. Among authors: hunt cm. Drug Saf. 2023 Feb;46(2):129-143. doi: 10.1007/s40264-022-01255-3. Epub 2022 Dec 22. Drug Saf. 2023. PMID: 36547811
APOL1 Risk Variants, Acute Kidney Injury, and Death in Participants With African Ancestry Hospitalized With COVID-19 From the Million Veteran Program.
Hung AM, Shah SC, Bick AG, Yu Z, Chen HC, Hunt CM, Wendt F, Wilson O, Greevy RA, Chung CP, Suzuki A, Ho YL, Akwo E, Polimanti R, Zhou J, Reaven P, Tsao PS, Gaziano JM, Huffman JE, Joseph J, Luoh SW, Iyengar S, Chang KM, Casas JP, Matheny ME, O'Donnell CJ, Cho K, Tao R, Susztak K, Robinson-Cohen C, Tuteja S, Siew ED; VA Million Veteran Program COVID-19 Science Initiative. Hung AM, et al. Among authors: hunt cm. JAMA Intern Med. 2022 Apr 1;182(4):386-395. doi: 10.1001/jamainternmed.2021.8538. JAMA Intern Med. 2022. PMID: 35089317 Free PMC article.
Pharmacogenetic variants and risk of remdesivir-associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID-19.
Tuteja S, Yu Z, Wilson O, Chen HC, Wendt F, Chung CP, Shah SC, Hunt CM, Suzuki A, Chanfreau C, Gorman BR, Joseph J, Luoh SW, Napolioni V, Robinson-Cohen C, Tao R, Zhou J, Chang KM, Hung AM; VA Million Veteran Program COVID-19 Science Initiative. Tuteja S, et al. Among authors: hunt cm. Clin Transl Sci. 2022 Aug;15(8):1880-1886. doi: 10.1111/cts.13313. Epub 2022 Jun 9. Clin Transl Sci. 2022. PMID: 35684976 Free PMC article.
A pre-marketing ALT signal predicts post-marketing liver safety.
Moylan CA, Suzuki A, Papay JI, Yuen NA, Ames M, Hunt CM. Moylan CA, et al. Among authors: hunt cm. Regul Toxicol Pharmacol. 2012 Aug;63(3):433-9. doi: 10.1016/j.yrtph.2012.05.016. Epub 2012 Jun 2. Regul Toxicol Pharmacol. 2012. PMID: 22668747
103 results