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Page 1
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.
Happ JT, Arveseth CD, Bruystens J, Bertinetti D, Nelson IB, Olivieri C, Zhang J, Hedeen DS, Zhu JF, Capener JL, Bröckel JW, Vu L, King CC, Ruiz-Perez VL, Ge X, Veglia G, Herberg FW, Taylor SS, Myers BR. Happ JT, et al. Among authors: bertinetti d. Nat Struct Mol Biol. 2022 Oct;29(10):990-999. doi: 10.1038/s41594-022-00838-z. Epub 2022 Oct 6. Nat Struct Mol Biol. 2022. PMID: 36202993 Free PMC article.
Chemical tools selectively target components of the PKA system.
Bertinetti D, Schweinsberg S, Hanke SE, Schwede F, Bertinetti O, Drewianka S, Genieser HG, Herberg FW. Bertinetti D, et al. Among authors: bertinetti o. BMC Chem Biol. 2009 Feb 12;9:3. doi: 10.1186/1472-6769-9-3. BMC Chem Biol. 2009. PMID: 19216744 Free PMC article.
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Huang GY, et al. Among authors: bertinetti d. Structure. 2014 Jan 7;22(1):116-24. doi: 10.1016/j.str.2013.09.021. Epub 2013 Nov 14. Structure. 2014. PMID: 24239458 Free PMC article.
42 results