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Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation.
Verma A, Hawes CE, Lakshmanappa YS, Roh JW, Schmidt BA, Dutra J, Louie W, Liu H, Ma ZM, Watanabe JK, Usachenko JL, Immareddy R, Sammak RL, Pollard R, Reader JR, Olstad KJ, Coffey LL, Kozlowski PA, Hartigan-O'Connor DJ, Nussenzweig M, Van Rompay KKA, Morrison JH, Iyer SS. Verma A, et al. Among authors: hawes ce. Cell Rep. 2021 Nov 2;37(5):109942. doi: 10.1016/j.celrep.2021.109942. Epub 2021 Oct 19. Cell Rep. 2021. PMID: 34706272 Free PMC article.
Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C HIV-1 Vaccine in Rhesus Macaques.
Verma A, Hawes CE, Elizaldi SR, Smith JC, Rajasundaram D, Pedersen GK, Shen X, Williams LD, Tomaras GD, Kozlowski PA, Amara RR, Iyer SS. Verma A, et al. Among authors: hawes ce. bioRxiv [Preprint]. 2023 Nov 2:2023.07.18.549515. doi: 10.1101/2023.07.18.549515. bioRxiv. 2023. Update in: Elife. 2024 Feb 22;12:RP89395. doi: 10.7554/eLife.89395 PMID: 37503150 Free PMC article. Updated. Preprint.
CCR7+ CD4 T Cell Immunosurveillance Disrupted in Chronic SIV-Induced Neuroinflammation in Rhesus Brain.
Elizaldi SR, Hawes CE, Verma A, Dinasarapu AR, Lakshmanappa YS, Schlegel BT, Rajasundaram D, Li J, Durbin-Johnson BP, Ma ZM, Beckman D, Ott S, Lifson J, Morrison JH, Iyer SS. Elizaldi SR, et al. Among authors: hawes ce. bioRxiv [Preprint]. 2023 Aug 31:2023.08.28.555037. doi: 10.1101/2023.08.28.555037. bioRxiv. 2023. Update in: J Clin Invest. 2024 Mar 12;134(9):e175332. doi: 10.1172/JCI175332 PMID: 37693567 Free PMC article. Updated. Preprint.
Deep analysis of CD4 T cells in the rhesus CNS during SIV infection.
Elizaldi SR, Verma A, Ma ZM, Ott S, Rajasundaram D, Hawes CE, Lakshmanappa YS, Cottrell ML, Kashuba ADM, Ambrose Z, Lifson JD, Morrison JH, Iyer SS. Elizaldi SR, et al. Among authors: hawes ce. PLoS Pathog. 2023 Dec 7;19(12):e1011844. doi: 10.1371/journal.ppat.1011844. eCollection 2023 Dec. PLoS Pathog. 2023. PMID: 38060615 Free PMC article.
Chronic SIV-Induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain.
Elizaldi SR, Hawes CE, Verma A, Shaan Lakshmanappa Y, Dinasarapu AR, Schlegel BT, Rajasundaram D, Li J, Durbin-Johnson BP, Ma ZM, Pal PB, Beckman D, Ott S, Raeman R, Lifson J, Morrison JH, Iyer SS. Elizaldi SR, et al. Among authors: hawes ce. J Clin Invest. 2024 Mar 12;134(9):e175332. doi: 10.1172/JCI175332. J Clin Invest. 2024. PMID: 38470479 Free PMC article.