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Page 1
Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.
Lyu J, Liu Y, Gong L, Chen M, Madanat YF, Zhang Y, Cai F, Gu Z, Cao H, Kaphle P, Kim YJ, Kalkan FN, Stephens H, Dickerson KE, Ni M, Chen W, Patel P, Mims AS, Borate U, Burd A, Cai SF, Yin CC, You MJ, Chung SS, Collins RH, DeBerardinis RJ, Liu X, Xu J. Lyu J, et al. Among authors: deberardinis rj. Cancer Discov. 2023 Jan 9;13(1):170-193. doi: 10.1158/2159-8290.CD-21-1661. Cancer Discov. 2023. PMID: 36222845 Free PMC article.
Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.
Eskiocak B, McMillan EA, Mendiratta S, Kollipara RK, Zhang H, Humphries CG, Wang C, Garcia-Rodriguez J, Ding M, Zaman A, Rosales TI, Eskiocak U, Smith MP, Sudderth J, Komurov K, Deberardinis RJ, Wellbrock C, Davies MA, Wargo JA, Yu Y, De Brabander JK, Williams NS, Chin L, Rizos H, Long GV, Kittler R, White MA. Eskiocak B, et al. Among authors: deberardinis rj. Cancer Discov. 2017 Aug;7(8):832-851. doi: 10.1158/2159-8290.CD-16-0955. Epub 2017 Apr 28. Cancer Discov. 2017. PMID: 28455392 Free PMC article.
Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers.
Huang F, Ni M, Chalishazar MD, Huffman KE, Kim J, Cai L, Shi X, Cai F, Zacharias LG, Ireland AS, Li K, Gu W, Kaushik AK, Liu X, Gazdar AF, Oliver TG, Minna JD, Hu Z, DeBerardinis RJ. Huang F, et al. Among authors: deberardinis rj. Cell Metab. 2018 Sep 4;28(3):369-382.e5. doi: 10.1016/j.cmet.2018.06.005. Epub 2018 Jun 28. Cell Metab. 2018. PMID: 30043754 Free PMC article.
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Gu Z, Liu Y, Cai F, Patrick M, Zmajkovic J, Cao H, Zhang Y, Tasdogan A, Chen M, Qi L, Liu X, Li K, Lyu J, Dickerson KE, Chen W, Ni M, Merritt ME, Morrison SJ, Skoda RC, DeBerardinis RJ, Xu J. Gu Z, et al. Among authors: deberardinis rj. Cancer Discov. 2019 Sep;9(9):1228-1247. doi: 10.1158/2159-8290.CD-19-0152. Epub 2019 Jun 12. Cancer Discov. 2019. PMID: 31189531 Free PMC article.
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer.
Huang F, Huffman KE, Wang Z, Wang X, Li K, Cai F, Yang C, Cai L, Shih TS, Zacharias LG, Chung A, Yang Q, Chalishazar MD, Ireland AS, Stewart CA, Cargill K, Girard L, Liu Y, Ni M, Xu J, Wu X, Zhu H, Drapkin B, Byers LA, Oliver TG, Gazdar AF, Minna JD, DeBerardinis RJ. Huang F, et al. Among authors: deberardinis rj. J Clin Invest. 2021 Jan 4;131(1):e139929. doi: 10.1172/JCI139929. J Clin Invest. 2021. PMID: 33079728 Free PMC article.
Mitochondrial NADP+ is essential for proline biosynthesis during cell growth.
Tran DH, Kesavan R, Rion H, Soflaee MH, Solmonson A, Bezwada D, Vu HS, Cai F, Phillips JA 3rd, DeBerardinis RJ, Hoxhaj G. Tran DH, et al. Among authors: deberardinis rj. Nat Metab. 2021 Apr;3(4):571-585. doi: 10.1038/s42255-021-00374-y. Epub 2021 Apr 8. Nat Metab. 2021. PMID: 33833463 Free PMC article.
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis.
Patrick M, Gu Z, Zhang G, Wynn RM, Kaphle P, Cao H, Vu H, Cai F, Gao X, Zhang Y, Chen M, Ni M, Chuang DT, DeBerardinis RJ, Xu J. Patrick M, et al. Among authors: deberardinis rj. Nat Metab. 2022 Dec;4(12):1775-1791. doi: 10.1038/s42255-022-00689-4. Epub 2022 Nov 28. Nat Metab. 2022. PMID: 36443523
299 results