Yousef RG - Search Results

1

Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies.

Elkaeed EB, Yousef RG, Khalifa MM, Ibrahim A, Mehany ABM, Gobaara IMM, Alsfouk BA, Eldehna WM, Metwaly AM, Eissa IH, El-Zahabi MA. Elkaeed EB, et al. Among authors: yousef rg. Molecules. 2022 Sep 21;27(19):6203. doi: 10.3390/molecules27196203. Molecules. 2022. PMID: 36234734 Free PMC article.

2

Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation.

El-Adl K, Sakr HM, Yousef RG, Mehany ABM, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Abulkhair HS, Eissa IH. El-Adl K, et al. Among authors: yousef rg. Bioorg Chem. 2021 Sep;114:105105. doi: 10.1016/j.bioorg.2021.105105. Epub 2021 Jun 18. Bioorg Chem. 2021. PMID: 34175720

3

Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation.

Ran F, Li W, Qin Y, Yu T, Liu Z, Zhou M, Liu C, Qiao T, Li X, Yousef RG, Eissa IH, Khalifa MM. Ran F, et al. Among authors: yousef rg. Oxid Med Cell Longev. 2021 Oct 28;2021:8321400. doi: 10.1155/2021/8321400. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34745424 Free PMC article.

4

New quinoxalin-2(1H)-one-derived VEGFR-2 inhibitors: Design, synthesis, in vitro anticancer evaluations, in silico ADMET, and docking studies.

El-Adl K, Sakr HM, Yousef RG, Mehany ABM, Abulkhair HS, Eissa IH. El-Adl K, et al. Among authors: yousef rg. Arch Pharm (Weinheim). 2022 Jul;355(7):e2200048. doi: 10.1002/ardp.202200048. Epub 2022 Apr 18. Arch Pharm (Weinheim). 2022. PMID: 35437829

5

Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies.

Yousef RG, Ibrahim A, Khalifa MM, Eldehna WM, Gobaara IMM, Mehany ABM, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Yousef RG, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1389-1403. doi: 10.1080/14756366.2022.2070744. J Enzyme Inhib Med Chem. 2022. PMID: 35577416 Free PMC article.

6

Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2.

Yousef RG, Eldehna WM, Elwan A, Abdelaziz AS, Mehany ABM, Gobaara IMM, Alsfouk BA, Elkaeed EB, Metwaly AM, Eissa IH. Yousef RG, et al. Molecules. 2022 Jun 24;27(13):4079. doi: 10.3390/molecules27134079. Molecules. 2022. PMID: 35807326 Free PMC article.

7

Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects.

Elkaeed EB, Yousef RG, Elkady H, Gobaara IMM, Alsfouk BA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: yousef rg. Molecules. 2022 Jul 19;27(14):4606. doi: 10.3390/molecules27144606. Molecules. 2022. PMID: 35889478 Free PMC article.

8

Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies.

Yousef RG, Elwan A, Gobaara IMM, Mehany ABM, Eldehna WM, El-Metwally SA, A Alsfouk B, Elkaeed EB, Metwaly AM, Eissa IH. Yousef RG, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2206-2222. doi: 10.1080/14756366.2022.2110868. J Enzyme Inhib Med Chem. 2022. PMID: 35980113 Free PMC article.

9

New Anticancer Theobromine Derivative Targeting EGFR^WT and EGFR^T790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies.

Elkaeed EB, Yousef RG, Elkady H, Alsfouk AA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: yousef rg. Molecules. 2022 Sep 9;27(18):5859. doi: 10.3390/molecules27185859. Molecules. 2022. PMID: 36144596 Free PMC article.

10

In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative.

Elkaeed EB, Yousef RG, Elkady H, Mehany ABM, Alsfouk BA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: yousef rg. J Biomol Struct Dyn. 2023 Sep-Oct;41(16):7986-8001. doi: 10.1080/07391102.2022.2127907. Epub 2022 Oct 2. J Biomol Struct Dyn. 2023. PMID: 36184591

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