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Page 1
Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection.
Kabat AM, Hackl A, Sanin DE, Zeis P, Grzes KM, Baixauli F, Kyle R, Caputa G, Edwards-Hicks J, Villa M, Rana N, Curtis JD, Castoldi A, Cupovic J, Dreesen L, Sibilia M, Pospisilik JA, Urban JF Jr, Grün D, Pearce EL, Pearce EJ. Kabat AM, et al. Sci Immunol. 2022 Oct 21;7(76):eadd3263. doi: 10.1126/sciimmunol.add3263. Epub 2022 Oct 14. Sci Immunol. 2022. PMID: 36240286
Inflammation by way of macrophage metabolism.
Kabat AM, Pearce EJ. Kabat AM, et al. Science. 2017 May 5;356(6337):488-489. doi: 10.1126/science.aan2691. Science. 2017. PMID: 28473549 No abstract available.
Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2.
Sanin DE, Matsushita M, Klein Geltink RI, Grzes KM, van Teijlingen Bakker N, Corrado M, Kabat AM, Buck MD, Qiu J, Lawless SJ, Cameron AM, Villa M, Baixauli F, Patterson AE, Hässler F, Curtis JD, O'Neill CM, O'Sullivan D, Wu D, Mittler G, Huang SC, Pearce EL, Pearce EJ. Sanin DE, et al. Among authors: kabat am. Immunity. 2018 Dec 18;49(6):1021-1033.e6. doi: 10.1016/j.immuni.2018.10.011. Immunity. 2018. PMID: 30566880 Free PMC article.
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.
Puleston DJ, Buck MD, Klein Geltink RI, Kyle RL, Caputa G, O'Sullivan D, Cameron AM, Castoldi A, Musa Y, Kabat AM, Zhang Y, Flachsmann LJ, Field CS, Patterson AE, Scherer S, Alfei F, Baixauli F, Austin SK, Kelly B, Matsushita M, Curtis JD, Grzes KM, Villa M, Corrado M, Sanin DE, Qiu J, Pällman N, Paz K, Maccari ME, Blazar BR, Mittler G, Buescher JM, Zehn D, Rospert S, Pearce EJ, Balabanov S, Pearce EL. Puleston DJ, et al. Among authors: kabat am. Cell Metab. 2019 Aug 6;30(2):352-363.e8. doi: 10.1016/j.cmet.2019.05.003. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130465 Free PMC article.
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy.
Klein Geltink RI, Edwards-Hicks J, Apostolova P, O'Sullivan D, Sanin DE, Patterson AE, Puleston DJ, Ligthart NAM, Buescher JM, Grzes KM, Kabat AM, Stanczak M, Curtis JD, Hässler F, Uhl FM, Fabri M, Zeiser R, Pearce EJ, Pearce EL. Klein Geltink RI, et al. Among authors: kabat am. Nat Metab. 2020 Aug;2(8):703-716. doi: 10.1038/s42255-020-0256-z. Epub 2020 Aug 3. Nat Metab. 2020. PMID: 32747793 Free PMC article.
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors.
Zeis P, Lian M, Fan X, Herman JS, Hernandez DC, Gentek R, Elias S, Symowski C, Knöpper K, Peltokangas N, Friedrich C, Doucet-Ladeveze R, Kabat AM, Locksley RM, Voehringer D, Bajenoff M, Rudensky AY, Romagnani C, Grün D, Gasteiger G. Zeis P, et al. Among authors: kabat am. Immunity. 2020 Oct 13;53(4):775-792.e9. doi: 10.1016/j.immuni.2020.09.002. Epub 2020 Sep 30. Immunity. 2020. PMID: 33002412 Free PMC article.
IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection.
Montes de Oca M, de Labastida Rivera F, Winterford C, Frame TCM, Ng SS, Amante FH, Edwards CL, Bukali L, Wang Y, Uzonna JE, Kuns RD, Zhang P, Kabat A, Klein Geltink RI, Pearce EJ, Hill GR, Engwerda CR. Montes de Oca M, et al. PLoS Pathog. 2020 Oct 13;16(10):e1008994. doi: 10.1371/journal.ppat.1008994. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33049000 Free PMC article.
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity.
Corrado M, Edwards-Hicks J, Villa M, Flachsmann LJ, Sanin DE, Jacobs M, Baixauli F, Stanczak M, Anderson E, Azuma M, Quintana A, Curtis JD, Clapes T, Grzes KM, Kabat AM, Kyle R, Patterson AE, Geltink RK, Amulic B, Steward CG, Strathdee D, Trompouki E, O'Sullivan D, Pearce EJ, Pearce EL. Corrado M, et al. Among authors: kabat am. Cell Metab. 2020 Dec 1;32(6):981-995.e7. doi: 10.1016/j.cmet.2020.11.003. Cell Metab. 2020. PMID: 33264603 Free PMC article.
Fever supports CD8+ effector T cell responses by promoting mitochondrial translation.
O'Sullivan D, Stanczak MA, Villa M, Uhl FM, Corrado M, Klein Geltink RI, Sanin DE, Apostolova P, Rana N, Edwards-Hicks J, Grzes KM, Kabat AM, Kyle RL, Fabri M, Curtis JD, Buck MD, Patterson AE, Regina A, Field CS, Baixauli F, Puleston DJ, Pearce EJ, Zeiser R, Pearce EL. O'Sullivan D, et al. Among authors: kabat am. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2023752118. doi: 10.1073/pnas.2023752118. Epub 2021 Jun 14. Proc Natl Acad Sci U S A. 2021. PMID: 34161266 Free PMC article.
Polyamine metabolism is a central determinant of helper T cell lineage fidelity.
Puleston DJ, Baixauli F, Sanin DE, Edwards-Hicks J, Villa M, Kabat AM, Kamiński MM, Stanckzak M, Weiss HJ, Grzes KM, Piletic K, Field CS, Corrado M, Haessler F, Wang C, Musa Y, Schimmelpfennig L, Flachsmann L, Mittler G, Yosef N, Kuchroo VK, Buescher JM, Balabanov S, Pearce EJ, Green DR, Pearce EL. Puleston DJ, et al. Among authors: kabat am. Cell. 2021 Aug 5;184(16):4186-4202.e20. doi: 10.1016/j.cell.2021.06.007. Epub 2021 Jul 2. Cell. 2021. PMID: 34216540 Free PMC article.
29 results