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Page 1
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. Gong GQ, et al. Among authors: pinotsis n. Nature. 2023 Jun;618(7963):159-168. doi: 10.1038/s41586-023-05972-2. Epub 2023 May 24. Nature. 2023. PMID: 37225977 Free PMC article.
Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1.
Hartley AM, Lukoyanova N, Zhang Y, Cabrera-Orefice A, Arnold S, Meunier B, Pinotsis N, Maréchal A. Hartley AM, et al. Among authors: pinotsis n. Nat Struct Mol Biol. 2019 Jan;26(1):78-83. doi: 10.1038/s41594-018-0172-z. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598554 Free PMC article.
Evasion of cGAS and TRIM5 defines pandemic HIV.
Zuliani-Alvarez L, Govasli ML, Rasaiyaah J, Monit C, Perry SO, Sumner RP, McAlpine-Scott S, Dickson C, Rifat Faysal KM, Hilditch L, Miles RJ, Bibollet-Ruche F, Hahn BH, Boecking T, Pinotsis N, James LC, Jacques DA, Towers GJ. Zuliani-Alvarez L, et al. Among authors: pinotsis n. Nat Microbiol. 2022 Nov;7(11):1762-1776. doi: 10.1038/s41564-022-01247-0. Epub 2022 Oct 26. Nat Microbiol. 2022. PMID: 36289397 Free PMC article.
Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus.
Pinotsis N, Petoukhov M, Lange S, Svergun D, Zou P, Gautel M, Wilmanns M. Pinotsis N, et al. J Struct Biol. 2006 Aug;155(2):239-50. doi: 10.1016/j.jsb.2006.03.028. Epub 2006 Apr 27. J Struct Biol. 2006. PMID: 16713295
The level of complexity at this area is reflected by a large number of protein-protein interactions. Recently, we unraveled how the N-terminus of the longest filament component, the giant muscle protein titin, is assembled into an antiparallel (2:1) sandwich complex by the …
The level of complexity at this area is reflected by a large number of protein-protein interactions. Recently, we unraveled how the N …
Paxillin and ponsin interact in nascent costameres of muscle cells.
Gehmlich K, Pinotsis N, Hayess K, van der Ven PF, Milting H, El Banayosy A, Körfer R, Wilmanns M, Ehler E, Fürst DO. Gehmlich K, et al. Among authors: pinotsis n. J Mol Biol. 2007 Jun 8;369(3):665-82. doi: 10.1016/j.jmb.2007.03.050. Epub 2007 Mar 24. J Mol Biol. 2007. PMID: 17462669
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