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Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron.
Benlarbi M, Laroche G, Fink C, Fu K, Mulloy RP, Phan A, Ariana A, Stewart CM, Prévost J, Beaudoin-Bussières G, Daniel R, Bo Y, El Ferri O, Yockell-Lelièvre J, Stanford WL, Giguère PM, Mubareka S, Finzi A, Dekaban GA, Dikeakos JD, Côté M. Benlarbi M, et al. Among authors: giguere pm. iScience. 2022 Nov 18;25(11):105316. doi: 10.1016/j.isci.2022.105316. Epub 2022 Oct 10. iScience. 2022. PMID: 36254158 Free PMC article.
Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments.
Stewart CM, Phan A, Bo Y, LeBlond ND, Smith TKT, Laroche G, Giguère PM, Fullerton MD, Pelchat M, Kobasa D, Côté M. Stewart CM, et al. Among authors: giguere pm. PLoS Pathog. 2021 Jan 29;17(1):e1009275. doi: 10.1371/journal.ppat.1009275. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33513206 Free PMC article.
Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2.
Galipeau Y, Siragam V, Laroche G, Marion E, Greig M, McGuinty M, Booth RA, Durocher Y, Cuperlovic-Culf M, Bennett SAL, Crawley AM, Giguère PM, Cooper C, Langlois MA. Galipeau Y, et al. Among authors: giguere pm. EBioMedicine. 2021 Dec;74:103700. doi: 10.1016/j.ebiom.2021.103700. Epub 2021 Nov 30. EBioMedicine. 2021. PMID: 34861490 Free PMC article.
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.
Taha Z, Arulanandam R, Maznyi G, Godbout E, Carter-Timofte ME, Kurmasheva N, Reinert LS, Chen A, Crupi MJF, Boulton S, Laroche G, Phan A, Rezaei R, Alluqmani N, Jirovec A, Acal A, Fekete EEF, Singaravelu R, Petryk J, Idorn M, Potts KG, Todesco H, John C, Mahoney DJ, Ilkow CS, Giguère P, Alain T, Côté M, Paludan SR, Olagnier D, Bell JC, Azad T, Diallo JS. Taha Z, et al. Mol Ther. 2022 Sep 7;30(9):2998-3016. doi: 10.1016/j.ymthe.2022.04.025. Epub 2022 May 6. Mol Ther. 2022. PMID: 35526097 Free PMC article.
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models.
Rossotti MA, van Faassen H, Tran AT, Sheff J, Sandhu JK, Duque D, Hewitt M, Wen X, Bavananthasivam J, Beitari S, Matte K, Laroche G, Giguère PM, Gervais C, Stuible M, Guimond J, Perret S, Hussack G, Langlois MA, Durocher Y, Tanha J. Rossotti MA, et al. Among authors: giguere pm. Commun Biol. 2022 Sep 9;5(1):933. doi: 10.1038/s42003-022-03866-z. Commun Biol. 2022. PMID: 36085335 Free PMC article.
46 results