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TGM2-mediated histone transglutamination is dictated by steric accessibility.
Lukasak BJ, Mitchener MM, Kong L, Dul BE, Lazarus CD, Ramakrishnan A, Ni J, Shen L, Maze I, Muir TW. Lukasak BJ, et al. Among authors: ramakrishnan a. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2208672119. doi: 10.1073/pnas.2208672119. Epub 2022 Oct 18. Proc Natl Acad Sci U S A. 2022. PMID: 36256821 Free PMC article.
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I. Farrelly LA, et al. Among authors: ramakrishnan a. Nature. 2019 Mar;567(7749):535-539. doi: 10.1038/s41586-019-1024-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867594 Free PMC article.
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex.
Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, Montgomery SE, Loh YE, Labonté B, Conkey A, Symonds AE, Neve RL, Turecki G, Maze I, Dong Y, Zhang B, Shen L, Bagot RC, Nestler EJ. Lorsch ZS, et al. Among authors: ramakrishnan a. Nat Neurosci. 2019 Sep;22(9):1413-1423. doi: 10.1038/s41593-019-0462-8. Epub 2019 Aug 19. Nat Neurosci. 2019. PMID: 31427770 Free PMC article.
Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium.
Li J, Zhang T, Ramakrishnan A, Fritzsch B, Xu J, Wong EYM, Loh YE, Ding J, Shen L, Xu PX. Li J, et al. Among authors: ramakrishnan a. Nucleic Acids Res. 2020 Apr 6;48(6):2880-2896. doi: 10.1093/nar/gkaa012. Nucleic Acids Res. 2020. PMID: 31956913 Free PMC article.
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking.
Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, Turecki G, Shen L, Yan Z, Calipari ES, Dietz DM, Kenny PJ, Maze I. Lepack AE, et al. Among authors: ramakrishnan a. Science. 2020 Apr 10;368(6487):197-201. doi: 10.1126/science.aaw8806. Science. 2020. PMID: 32273471 Free PMC article.
392 results