Woodson ME - Search Results

1

Design, synthesis, and biological evaluation of novel sulfamoylbenzamide derivatives as HBV capsid assembly modulators.

Wang S, Ren Y, Li Q, Wang Y, Jiang X, Xu S, Zhang X, Zhao S, Bradley DP, Woodson ME, Zhao F, Wu S, Li Y, Tian Y, Liu X, Tavis JE, Zhan P. Wang S, et al. Among authors: woodson me. Bioorg Chem. 2022 Dec;129:106192. doi: 10.1016/j.bioorg.2022.106192. Epub 2022 Oct 13. Bioorg Chem. 2022. PMID: 36265355 Free PMC article.

2

Design, synthesis and evaluation of heteroaryldihydropyrimidine analogues bearing spiro ring as hepatitis B virus capsid protein inhibitors.

Ma Y, Zhao S, Ren Y, Cherukupalli S, Li Q, Woodson ME, Bradley DP, Tavis JE, Liu X, Zhan P. Ma Y, et al. Among authors: woodson me. Eur J Med Chem. 2021 Dec 5;225:113780. doi: 10.1016/j.ejmech.2021.113780. Epub 2021 Aug 19. Eur J Med Chem. 2021. PMID: 34438123 Free PMC article.

3

Efficient Inhibition of Hepatitis B Virus (HBV) Replication and cccDNA Formation by HBV Ribonuclease H Inhibitors during Infection.

Chauhan R, Li Q, Woodson ME, Gasonoo M, Meyers MJ, Tavis JE. Chauhan R, et al. Among authors: woodson me. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0146021. doi: 10.1128/AAC.01460-21. Epub 2021 Sep 13. Antimicrob Agents Chemother. 2021. PMID: 34516242 Free PMC article.

4

Effects of Troponoids on Mitochondrial Function and Cytotoxicity.

Bradley DP, O'Dea AT, Woodson ME, Li Q, Ponzar NL, Knier A, Rogers BL, Murelli RP, Tavis JE. Bradley DP, et al. Among authors: woodson me. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0161721. doi: 10.1128/AAC.01617-21. Epub 2021 Oct 25. Antimicrob Agents Chemother. 2022. PMID: 34694883 Free PMC article.

5

Synthesis of Polyoxygenated Tropolones and their Antiviral Activity against Hepatitis B Virus and Herpes Simplex Virus-1.

Schiavone DV, Kapkayeva DM, Li Q, Woodson ME, Gazquez Casals A, Morrison LA, Tavis JE, Murelli RP. Schiavone DV, et al. Among authors: woodson me. Chemistry. 2022 Feb 21;28(10):e202104112. doi: 10.1002/chem.202104112. Epub 2022 Jan 31. Chemistry. 2022. PMID: 34984767 Free PMC article.

6

Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity.

Gao S, Sylvester K, Song L, Claff T, Jing L, Woodson M, Weiße RH, Cheng Y, Schäkel L, Petry M, Gütschow M, Schiedel AC, Sträter N, Kang D, Xu S, Toth K, Tavis J, Tollefson AE, Müller CE, Liu X, Zhan P. Gao S, et al. J Med Chem. 2022 Oct 13;65(19):13343-13364. doi: 10.1021/acs.jmedchem.2c01146. Epub 2022 Sep 15. J Med Chem. 2022. PMID: 36107752

7

Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors.

Gao S, Song L, Claff T, Woodson M, Sylvester K, Jing L, Weiße RH, Cheng Y, Sträter N, Schäkel L, Gütschow M, Ye B, Yang M, Zhang T, Kang D, Toth K, Tavis J, Tollefson AE, Müller CE, Zhan P, Liu X. Gao S, et al. J Med Chem. 2022 Dec 22;65(24):16902-16917. doi: 10.1021/acs.jmedchem.2c01716. Epub 2022 Dec 7. J Med Chem. 2022. PMID: 36475694

8

Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening.

Jiang X, Li J, Viayna A, Luque FJ, Woodson M, Jing L, Gao S, Zhao F, Xie M, Toth K, Tavis J, Tollefson AE, Liu X, Zhan P. Jiang X, et al. RSC Med Chem. 2023 Aug 17;14(10):2068-2078. doi: 10.1039/d3md00306j. eCollection 2023 Oct 18. RSC Med Chem. 2023. PMID: 37859715 Free PMC article.

9

In vitro evaluation of tropolone absorption, metabolism, and clearance.

Woodson ME, Mottaleb MA, Murelli RP, Tavis JE. Woodson ME, et al. Antiviral Res. 2023 Dec;220:105762. doi: 10.1016/j.antiviral.2023.105762. Epub 2023 Nov 22. Antiviral Res. 2023. PMID: 37996012 Free PMC article.

10

Identification and assessment of the 1,6-dihydroxy-pyridin-2-one moiety as privileged scaffold for HBV ribonuclease H inhibition.

Giannakopoulou E, Pardali V, Edwards TC, Woodson M, Tajwar R, Tavis JE, Zoidis G. Giannakopoulou E, et al. Antiviral Res. 2024 Mar;223:105833. doi: 10.1016/j.antiviral.2024.105833. Epub 2024 Feb 5. Antiviral Res. 2024. PMID: 38325606 Free PMC article.

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