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HIRA loss transforms FH-deficient cells.
Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Valcarcel-Jimenez L, et al. Among authors: frezza c. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269833 Free PMC article.
Germline FH mutations presenting with pheochromocytoma.
Clark GR, Sciacovelli M, Gaude E, Walsh DM, Kirby G, Simpson MA, Trembath RC, Berg JN, Woodward ER, Kinning E, Morrison PJ, Frezza C, Maher ER. Clark GR, et al. Among authors: frezza c. J Clin Endocrinol Metab. 2014 Oct;99(10):E2046-50. doi: 10.1210/jc.2014-1659. Epub 2014 Jul 8. J Clin Endocrinol Metab. 2014. PMID: 25004247
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Sciacovelli M, Gonçalves E, Johnson TI, Zecchini VR, da Costa AS, Gaude E, Drubbel AV, Theobald SJ, Abbo SR, Tran MG, Rajeeve V, Cardaci S, Foster S, Yun H, Cutillas P, Warren A, Gnanapragasam V, Gottlieb E, Franze K, Huntly B, Maher ER, Maxwell PH, Saez-Rodriguez J, Frezza C. Sciacovelli M, et al. Among authors: frezza c. Nature. 2016 Aug 31;537(7621):544-547. doi: 10.1038/nature19353. Nature. 2016. PMID: 27580029 Free PMC article.
Mitochondrial Metabolism: Yin and Yang for Tumor Progression.
Valcarcel-Jimenez L, Gaude E, Torrano V, Frezza C, Carracedo A. Valcarcel-Jimenez L, et al. Among authors: frezza c. Trends Endocrinol Metab. 2017 Oct;28(10):748-757. doi: 10.1016/j.tem.2017.06.004. Trends Endocrinol Metab. 2017. PMID: 28938972 Free PMC article. Review.
Fumarate hydratase in cancer: A multifaceted tumour suppressor.
Schmidt C, Sciacovelli M, Frezza C. Schmidt C, et al. Among authors: frezza c. Semin Cell Dev Biol. 2020 Feb;98:15-25. doi: 10.1016/j.semcdb.2019.05.002. Epub 2019 May 22. Semin Cell Dev Biol. 2020. PMID: 31085323 Free PMC article. Review.
Oncometabolites in renal cancer.
Yong C, Stewart GD, Frezza C. Yong C, et al. Among authors: frezza c. Nat Rev Nephrol. 2020 Mar;16(3):156-172. doi: 10.1038/s41581-019-0210-z. Epub 2019 Oct 21. Nat Rev Nephrol. 2020. PMID: 31636445 Free PMC article. Review.
Crosstalk between mechanotransduction and metabolism.
Romani P, Valcarcel-Jimenez L, Frezza C, Dupont S. Romani P, et al. Among authors: frezza c. Nat Rev Mol Cell Biol. 2021 Jan;22(1):22-38. doi: 10.1038/s41580-020-00306-w. Epub 2020 Nov 13. Nat Rev Mol Cell Biol. 2021. PMID: 33188273 Review.
245 results