Yang K - Search Results

1

Discovery of selective covalent cathepsin K inhibitors containing novel 4-cyanopyrimidine warhead based on quantum chemical calculations and binding mode analysis.

Jia Y, Wang K, Wang H, Zhang B, Yang K, Zhang Z, Dong H, Wang J. Jia Y, et al. Among authors: yang k. Bioorg Med Chem. 2022 Nov 15;74:117053. doi: 10.1016/j.bmc.2022.117053. Epub 2022 Oct 9. Bioorg Med Chem. 2022. PMID: 36270112

2

Anticarcinogenic Effects of α-Mangostin: A Review.

Zhang KJ, Gu QL, Yang K, Ming XJ, Wang JX. Zhang KJ, et al. Among authors: yang k. Planta Med. 2017 Feb;83(3-04):188-202. doi: 10.1055/s-0042-119651. Epub 2016 Nov 4. Planta Med. 2017. PMID: 27824406 Free article. Review.

3

Synthesis and evaluation of xanthone derivatives as acid sphingomyelinase inhibitors: potential treatment for UV-induced skin damage.

Yang K, Gao B, Ming X, Huang Z, Wang M, Dong J, Wang J. Yang K, et al. Future Med Chem. 2017 Oct;9(16):1887-1898. doi: 10.4155/fmc-2017-0102. Epub 2017 Oct 27. Future Med Chem. 2017. PMID: 29076348

4

Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model.

Yang K, Nong K, Gu Q, Dong J, Wang J. Yang K, et al. Eur J Med Chem. 2018 May 10;151:389-400. doi: 10.1016/j.ejmech.2018.03.065. Epub 2018 Mar 27. Eur J Med Chem. 2018. PMID: 29649738

5

Targeting sphingosine kinase 1 for the treatment of pulmonary arterial hypertension.

Yang K, Jiang K, Xu Z, Song Y, Wang J. Yang K, et al. Future Med Chem. 2019 Nov;11(22):2939-2953. doi: 10.4155/fmc-2019-0130. Epub 2019 Nov 12. Future Med Chem. 2019. PMID: 31713437 Review.

6

Discovery of Potent, Selective, and Direct Acid Sphingomyelinase Inhibitors with Antidepressant Activity.

Yang K, Yu J, Nong K, Wang Y, Niu A, Chen W, Dong J, Wang J. Yang K, et al. J Med Chem. 2020 Feb 13;63(3):961-974. doi: 10.1021/acs.jmedchem.9b00739. Epub 2020 Jan 28. J Med Chem. 2020. PMID: 31944697

7

Design, synthesis and evaluation of new 4-arylthiazole-2-amine derivatives as acetylcholinesterase inhibitors.

Xu Y, Jian MM, Han C, Yang K, Bai LG, Cao F, Ma ZY. Xu Y, et al. Among authors: yang k. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126985. doi: 10.1016/j.bmcl.2020.126985. Epub 2020 Jan 24. Bioorg Med Chem Lett. 2020. PMID: 32008906

8

Recent progress of palmitoyl transferase DHHC3 as a novel antitumor target.

Gao T, Liu S, Li X, Qin Z, Wang K, Wang J, Song Y, Yang K. Gao T, et al. Among authors: yang k. Future Med Chem. 2022 Mar;14(6):443-455. doi: 10.4155/fmc-2021-0192. Epub 2022 Feb 8. Future Med Chem. 2022. PMID: 35134300 Review.

9

Development of indole-2-carbonyl piperazine urea derivatives as selective FAAH inhibitors for efficient treatment of depression and pain.

Shang Y, Wang M, Hao Q, Meng T, Li L, Shi J, Yang G, Zhang Z, Yang K, Wang J. Shang Y, et al. Among authors: yang k, yang g. Bioorg Chem. 2022 Nov;128:106031. doi: 10.1016/j.bioorg.2022.106031. Epub 2022 Jul 16. Bioorg Chem. 2022. PMID: 36037600

10

Sappanone A: A natural PDE4 inhibitor with dual anti-inflammatory and antioxidant activities from the heartwood of Caesalpinia sappan L.

Wang YZ, Wang YL, Che HJ, Jia YH, Wang HF, Zuo LF, Yang K, Li TT, Wang JX. Wang YZ, et al. Among authors: yang k. J Ethnopharmacol. 2023 Mar 25;304:116020. doi: 10.1016/j.jep.2022.116020. Epub 2022 Dec 16. J Ethnopharmacol. 2023. PMID: 36529254

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