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Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics.
Giles JR, Ngiow SF, Manne S, Baxter AE, Khan O, Wang P, Staupe R, Abdel-Hakeem MS, Huang H, Mathew D, Painter MM, Wu JE, Huang YJ, Goel RR, Yan PK, Karakousis GC, Xu X, Mitchell TC, Huang AC, Wherry EJ. Giles JR, et al. Among authors: wherry ej. Nat Immunol. 2022 Nov;23(11):1600-1613. doi: 10.1038/s41590-022-01338-4. Epub 2022 Oct 21. Nat Immunol. 2022. PMID: 36271148 Free PMC article.
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.
Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, Goldrath AW, Ahmed R, Reiner SL. Intlekofer AM, et al. Among authors: wherry ej. Nat Immunol. 2005 Dec;6(12):1236-44. doi: 10.1038/ni1268. Epub 2005 Nov 6. Nat Immunol. 2005. PMID: 16273099
CD8 T cell dysfunction during chronic viral infection.
Shin H, Wherry EJ. Shin H, et al. Among authors: wherry ej. Curr Opin Immunol. 2007 Aug;19(4):408-15. doi: 10.1016/j.coi.2007.06.004. Epub 2007 Jul 25. Curr Opin Immunol. 2007. PMID: 17656078 Review.
352 results