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HepaCAM inhibits the malignant behavior of castration-resistant prostate cancer cells by downregulating Notch signaling and PF-3084014 (a γ-secretase inhibitor) partly reverses the resistance of refractory prostate cancer to docetaxel and enzalutamide in vitro.
Du Z, Li L, Sun W, Wang X, Zhang Y, Chen Z, Yuan M, Quan Z, Liu N, Hao Y, Li T, Wang J, Luo C, Wu X. Du Z, et al. Among authors: li t, li l. Int J Oncol. 2018 Jul;53(1):99-112. doi: 10.3892/ijo.2018.4370. Epub 2018 Apr 12. Int J Oncol. 2018. PMID: 29658567 Free PMC article.
Inhibitor 9 Combined With Androgen Deprivation Therapy or Chemotherapy Delays the Malignant Behavior of Castration-Resistant Prostate Cancer Through K-Ras/PLCε/PKCε Signaling Pathway.
Liu J, Zheng Y, Gao Y, Quan Z, Qiao B, Li L, Li T, Duan L, Yang J, Luo C, Wu X. Liu J, et al. Among authors: li t, li l. Front Oncol. 2020 Feb 25;10:75. doi: 10.3389/fonc.2020.00075. eCollection 2020. Front Oncol. 2020. Retraction in: Front Oncol. 2021 May 31;11:707608. doi: 10.3389/fonc.2021.707608 PMID: 32158687 Free PMC article. Retracted.
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