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Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.
Vernia S, Lee A, Kennedy NJ, Han MS, Isasa M, Cavanagh-Kyros J, Roy A, Syed A, Chaudhry S, Edwards YJK, Gygi SP, Gao G, Davis RJ. Vernia S, et al. Among authors: edwards yjk. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2210434119. doi: 10.1073/pnas.2210434119. Epub 2022 Oct 25. Proc Natl Acad Sci U S A. 2022. PMID: 36282921 Free PMC article.
The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in pre-cystic epithelial cells revealing a new target for polycystic kidney disease.
Smith AO, Frantz WT, Preval KM, Edwards YJK, Ceol CJ, Jonassen JA, Pazour GJ. Smith AO, et al. Among authors: edwards yjk. medRxiv [Preprint]. 2023 Dec 4:2023.12.04.23299387. doi: 10.1101/2023.12.04.23299387. medRxiv. 2023. Update in: PLoS Genet. 2024 Dec 12;20(12):e1011510. doi: 10.1371/journal.pgen.1011510 PMID: 38106222 Free PMC article. Updated. Preprint.
48 results