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Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease.
Elsesy ME, Oh-Hohenhorst SJ, Oing C, Eckhardt A, Burdak-Rothkamm S, Alawi M, Müller C, Schüller U, Maurer T, von Amsberg G, Petersen C, Rothkamm K, Mansour WY. Elsesy ME, et al. Among authors: rothkamm k. Mol Oncol. 2023 Jun;17(6):1129-1147. doi: 10.1002/1878-0261.13382. Epub 2023 Mar 16. Mol Oncol. 2023. PMID: 36694344 Free PMC article.
Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1.
Oetting A, Christiansen S, Gatzemeier F, Köcher S, Bußmann L, Böttcher A, Stölzel K, Hoffmann AS, Struve N, Kriegs M, Petersen C, Betz C, Rothkamm K, Zech HB, Rieckmann T. Oetting A, et al. Among authors: rothkamm k. Clin Transl Radiat Oncol. 2023 Apr 20;41:100630. doi: 10.1016/j.ctro.2023.100630. eCollection 2023 Jul. Clin Transl Radiat Oncol. 2023. PMID: 37180052 Free PMC article.
Mean global DNA methylation serves as independent prognostic marker in IDH-wildtype glioblastoma.
Eckhardt A, Drexler R, Schoof M, Struve N, Capper D, Jelgersma C, Onken J, Harter PN, Weber KJ, Divé I, Rothkamm K, Hoffer K, Klumpp L, Ganser K, Petersen C, Ricklefs F, Kriegs M, Schüller U. Eckhardt A, et al. Among authors: rothkamm k. Neuro Oncol. 2024 Mar 4;26(3):503-513. doi: 10.1093/neuonc/noad197. Neuro Oncol. 2024. PMID: 37818983 Free PMC article.
Trifluridine/Tipiracil Based Chemoradiation in locally Advanced Rectal Cancer: The Phase I/II TARC Trial.
Thiele B, Stein A, Schultheiß C, Paschold L, Jonas H, Goekkurt E, Rüssel J, Schuch G, Wierecky J, Sinn M, Tintelnot J, Petersen C, Rothkamm K, Vettorazzi E, Binder M. Thiele B, et al. Among authors: rothkamm k. Clin Colorectal Cancer. 2024 Jun 22:S1533-0028(24)00059-8. doi: 10.1016/j.clcc.2024.06.003. Online ahead of print. Clin Colorectal Cancer. 2024. PMID: 39003182 Free article.
Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance.
Classen S, Rahlf E, Jungwirth J, Albers N, Hebestreit LP, Zielinski A, Poole L, Groth M, Koch P, Liehr T, Kankel S, Cordes N, Petersen C, Rothkamm K, Pospiech H, Borgmann K. Classen S, et al. Among authors: rothkamm k. Int J Mol Sci. 2022 Nov 1;23(21):13363. doi: 10.3390/ijms232113363. Int J Mol Sci. 2022. PMID: 36362151 Free PMC article.
139 results