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Gut Pathobiont-Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis-Associated Inflammatory Bowel Disease.
Dorner H, Stolzer I, Mattner J, Kaminski S, Leistl S, Edrich LM, Schwendner R, Hobauer J, Sebald A, Leikam S, Gonzalez Acera M, Düll M, Lang R, Seidel G, Seitz T, Hellerbrand C, Fuhrmann G, Distler U, Tenzer S, Eichhorn P, Vieth M, Schramm C, Arnold P, Becker C, Weidinger C, Siegmund B, Atreya R, Leppkes M, Naschberger E, Sampaziotis F, Dietrich P, Rauh M, Wirtz S, Kremer AE, Neurath MF, Günther C. Dorner H, et al. Among authors: hellerbrand c. Gastroenterology. 2024 Nov;167(6):1183-1197.e16. doi: 10.1053/j.gastro.2024.06.032. Epub 2024 Jul 9. Gastroenterology. 2024. PMID: 38992449
Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1.
Ortiz C, Klein S, Reul WH, Magdaleno F, Gröschl S, Dietrich P, Schierwagen R, Uschner FE, Torres S, Hieber C, Meier C, Kraus N, Tyc O, Brol M, Zeuzem S, Welsch C, Poglitsch M, Hellerbrand C, Alfonso-Prieto M, Mira F, Keller UAD, Tetzner A, Moore A, Walther T, Trebicka J. Ortiz C, et al. Among authors: hellerbrand c. Cell Rep. 2023 Feb 28;42(2):112059. doi: 10.1016/j.celrep.2023.112059. Epub 2023 Jan 31. Cell Rep. 2023. PMID: 36729833 Free PMC article.
Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity.
Brummer C, Singer K, Brand A, Bruss C, Renner K, Herr W, Pukrop T, Dorn C, Hellerbrand C, Matos C, Kreutz M. Brummer C, et al. Among authors: hellerbrand c. Int J Mol Sci. 2024 Jul 28;25(15):8234. doi: 10.3390/ijms25158234. Int J Mol Sci. 2024. PMID: 39125804 Free PMC article.
Four-and-a-Half LIM-Domain Protein 2 (FHL2) Induces Neuropeptide Y (NPY) in Macrophages in Visceral Adipose Tissue and Promotes Diet-Induced Obesity.
Sommer J, Ehnis H, Seitz T, Schneider J, Wild AB, Moceri S, Buechler C, Bozec A, Weber GF, Merkel S, Beckervordersandforth R, Steinkasserer A, Schüle R, Trebicka J, Hartmann A, Bosserhoff A, von Hörsten S, Dietrich P, Hellerbrand C. Sommer J, et al. Among authors: hellerbrand c. Int J Mol Sci. 2023 Oct 6;24(19):14943. doi: 10.3390/ijms241914943. Int J Mol Sci. 2023. PMID: 37834391 Free PMC article.
258 results