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Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain.
Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. Birtele M, et al. Among authors: parmar m. Development. 2022 Dec 1;149(23):dev200504. doi: 10.1242/dev.200504. Epub 2022 Dec 8. Development. 2022. PMID: 36305490 Free PMC article.
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.
Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Grealish S, et al. Among authors: parmar m. Cell Stem Cell. 2014 Nov 6;15(5):653-65. doi: 10.1016/j.stem.2014.09.017. Epub 2014 Nov 6. Cell Stem Cell. 2014. PMID: 25517469 Free PMC article.
1,022 results