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31 results

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Page 1
p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.
Serra F, Nieto-Aliseda A, Fanlo-Escudero L, Rovirosa L, Cabrera-Pasadas M, Lazarenkov A, Urmeneta B, Alcalde-Merino A, Nola EM, Okorokov AL, Fraser P, Graupera M, Castillo SD, Sardina JL, Valencia A, Javierre BM. Serra F, et al. Among authors: sardina jl. Nat Commun. 2024 Apr 1;15(1):2821. doi: 10.1038/s41467-024-46666-1. Nat Commun. 2024. PMID: 38561401 Free PMC article.
NOX2 control over energy metabolism plays a role in acute myeloid leukaemia prognosis and survival.
Ijurko C, Romo-González M, García-Calvo C, Sardina JL, Sánchez-Bernal C, Sánchez-Yagüe J, Elena-Herrmann B, Villaret J, Garrel C, Mondet J, Mossuz P, Hernández-Hernández Á. Ijurko C, et al. Among authors: sardina jl. Free Radic Biol Med. 2023 Nov 20;209(Pt 1):18-28. doi: 10.1016/j.freeradbiomed.2023.10.013. Epub 2023 Oct 6. Free Radic Biol Med. 2023. PMID: 37806599 Free article.
NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression.
Lopez-Millan B, Rubio-Gayarre A, Vinyoles M, Trincado JL, Fraga MF, Fernandez-Fuentes N, Guerrero-Murillo M, Martinez A, Velasco-Hernandez T, Falgàs A, Panisello C, Valcarcel G, Sardina JL, López-Martí P, Javierre BM, Del Valle-Pérez B, García de Herreros A, Locatelli F, Pieters R, Bardini M, Cazzaniga G, Rodríguez-Manzaneque JC, Hanewald T, Marschalek R, Milne TA, Stam RW, Tejedor JR, Menendez P, Bueno C. Lopez-Millan B, et al. Among authors: sardina jl. Blood. 2024 Nov 7;144(19):2002-2017. doi: 10.1182/blood.2023022050. Blood. 2024. PMID: 39093982
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5.
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray JK, Ray C, Berenguer C, Kumari P, Bech JJ, Braun T, Ianni A, Tischfield JA, Serrano L, Esteller M, Sardina JL, De La Torre C, Sigvardsson M, Vazquez BN, Vaquero A. Gamez-Garcia A, et al. Among authors: sardina jl. Nat Immunol. 2024 Dec;25(12):2308-2319. doi: 10.1038/s41590-024-01995-7. Epub 2024 Oct 18. Nat Immunol. 2024. PMID: 39424985 Free PMC article.
RNA sequestration in P-bodies sustains myeloid leukaemia.
Kodali S, Proietti L, Valcarcel G, López-Rubio AV, Pessina P, Eder T, Shi J, Jen A, Lupión-Garcia N, Starner AC, Bartels MD, Cui Y, Sands CM, Planas-Riverola A, Martínez A, Velasco-Hernandez T, Tomás-Daza L, Alber B, Manhart G, Mayer IM, Kollmann K, Fatica A, Menendez P, Shishkova E, Rau RE, Javierre BM, Coon J, Chen Q, Van Nostrand EL, Sardina JL, Grebien F, Di Stefano B. Kodali S, et al. Among authors: sardina jl. Nat Cell Biol. 2024 Oct;26(10):1745-1758. doi: 10.1038/s41556-024-01489-6. Epub 2024 Aug 21. Nat Cell Biol. 2024. PMID: 39169219
The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development.
Azagra A, Meler A, de Barrios O, Tomás-Daza L, Collazo O, Monterde B, Obiols M, Rovirosa L, Vila-Casadesús M, Cabrera-Pasadas M, Gusi-Vives M, Graf T, Varela I, Sardina JL, Javierre BM, Parra M. Azagra A, et al. Among authors: sardina jl. Nucleic Acids Res. 2022 Aug 26;50(15):8471-8490. doi: 10.1093/nar/gkac619. Nucleic Acids Res. 2022. PMID: 35904805 Free PMC article.
Editorial: Chromatin Regulation in Cell Fate Decisions.
Brumbaugh J, Di Stefano B, Sardina JL. Brumbaugh J, et al. Among authors: sardina jl. Front Cell Dev Biol. 2021 Sep 1;9:734020. doi: 10.3389/fcell.2021.734020. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34540846 Free PMC article. No abstract available.
31 results