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1-Methyl-3-((4-(quinolin-4-yloxy)phenyl)amino)-1H-pyrazole-4-carboxamide derivatives as new rearranged during Transfection (RET) kinase inhibitors capable of suppressing resistant mutants in solvent-front regions.
Zhang Y, Chan S, He R, Liu Y, Song X, Tu ZC, Ren X, Zhou Y, Zhang Z, Wang Z, Zhou F, Ding K. Zhang Y, et al. Among authors: liu y. Eur J Med Chem. 2022 Dec 15;244:114862. doi: 10.1016/j.ejmech.2022.114862. Epub 2022 Oct 21. Eur J Med Chem. 2022. PMID: 36308779
Discovery of Hexahydrofuro[3,2-b]furans as New Kinase-Selective and Orally Bioavailable JAK3 Inhibitors for the Treatment of Leukemia Harboring a JAK3 Activating Mutant.
Li S, Si H, Song X, Lei C, He X, Wang J, Liu Y, Zhou Y, Song JG, Peng L, Tang X, Chan S, Ren X, Tu Z, Li Z, Wang Z, Zhang Z, Ding K. Li S, et al. Among authors: liu y. J Med Chem. 2022 Aug 11;65(15):10674-10690. doi: 10.1021/acs.jmedchem.2c00922. Epub 2022 Jul 20. J Med Chem. 2022. PMID: 35860875
Structure-Based Optimization of Pyrazinamide-Containing Macrocyclic Derivatives as Fms-like Tyrosine Kinase 3 (FLT3) Inhibitors to Overcome Clinical Mutations.
Zheng X, Chen Z, Guo M, Liang H, Song X, Liu Y, Liao Z, Zhang Y, Guo J, Zhou Y, Zhang ZM, Tu Z, Zhang Y, Chen Y, Zhang Z, Lu X. Zheng X, et al. Among authors: liu y. ACS Pharmacol Transl Sci. 2024 Apr 11;7(5):1485-1506. doi: 10.1021/acsptsci.4c00071. eCollection 2024 May 10. ACS Pharmacol Transl Sci. 2024. PMID: 38751627
Effects of stress hyperglycemia ratio upon long-lasting prognosis in coronary artery disease patients with or lacking chronic renal impairment: findings from a Chinese multi-center observational study.
Wu J, Liu J, Yuan Z, Tang S, Zhang W, Xiang Y, Chen J, Lin Q, Guo W, He Y, Huang H, Lu X, Deng J, Ruan H, Jiang R, Chen S, Liu Y. Wu J, et al. Among authors: liu y. Diabetol Metab Syndr. 2024 Dec 31;16(1):316. doi: 10.1186/s13098-024-01521-7. Diabetol Metab Syndr. 2024. PMID: 39741358
208,382 results
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