Effect of N-Methyl-pyrrolidone (NMP) on the Equilibrium Solubility of Meloxicam in Aqueous Media: Correlation, Dissolution Thermodynamics, and Preferential Solvation.
Tinjacá DA, Martínez F, Almanza OA, Jouyban A, Acree WE Jr.
Tinjacá DA, et al. Among authors: jouyban a.
ACS Omega. 2022 Oct 14;7(42):37988-38002. doi: 10.1021/acsomega.2c05189. eCollection 2022 Oct 25.
ACS Omega. 2022.
PMID: 36312332
Free PMC article.
The flask-shake method and UV-vis spectrophotometry were used for meloxicam solubility determination as a function of temperature and mixture composition. Several cosolvency models, including the Jouyban-Acree model, were challenged for equilibrium solubility correl …
The flask-shake method and UV-vis spectrophotometry were used for meloxicam solubility determination as a function of temperature and …