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A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.
Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, Osterman AL, Sengupta A, Weljie A, Huang M, Zhang D, Fan Y, Radaelli E, Tobias JW, Rambow F, Karras P, Marine JC, Xu X, Hatzigeorgiou AG, Ryeom S, Diehl JA, Fuchs SY, Puré E, Koumenis C. Verginadis II, et al. Among authors: bell bi. Nat Cell Biol. 2022 Jun;24(6):940-953. doi: 10.1038/s41556-022-00918-8. Epub 2022 Jun 2. Nat Cell Biol. 2022. PMID: 35654839 Free PMC article.
FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone.
Verginadis II, Velalopoulou A, Kim MM, Kim K, Paraskevaidis I, Bell B, Oliaei Motlagh SA, Karaj A, Banerjee E, Finesso G, Assenmacher CA, Radaelli E, Lu J, Lin Y, Putt ME, Diffenderfer ES, Guha C, Qin L, Metz JM, Maity A, Cengel KA, Koumenis C, Busch TM. Verginadis II, et al. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602528. doi: 10.1101/2024.07.08.602528. bioRxiv. 2024. PMID: 39026805 Free PMC article. Preprint.
Whole Abdominal Pencil Beam Scanned Proton FLASH Increases Acute Lethality.
Bell BI, Velten C, Pennock M, Kang M, Tanaka KE, Selvaraj B, Bookbinder A, Koba W, Vercellino J, English J, Małachowska B, Pandey S, Duddempudi PK, Yang Y, Shajahan S, Hasan S, Choi JI, Simone CB 2nd, Yang WL, Tomé WA, Lin H, Guha C. Bell BI, et al. Int J Radiat Oncol Biol Phys. 2025 Feb 1;121(2):493-505. doi: 10.1016/j.ijrobp.2024.09.006. Epub 2024 Sep 18. Int J Radiat Oncol Biol Phys. 2025. PMID: 39299552
Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation.
Bell BI, Vercellino J, Brodin NP, Velten C, Nanduri LSY, Nagesh PKB, Tanaka KE, Fang Y, Wang Y, Macedo R, English J, Schumacher MM, Duddempudi PK, Asp P, Koba W, Shajahan S, Liu L, Tomé WA, Yang WL, Kolesnick R, Guha C. Bell BI, et al. Cancer Res. 2022 Aug 3;82(15):2678-2691. doi: 10.1158/0008-5472.CAN-22-0656. Cancer Res. 2022. PMID: 35919990 Free PMC article.
14 results