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Page 1
FLASH Proton Radiation Therapy Mitigates Inflammatory and Fibrotic Pathways and Preserves Cardiac Function in a Preclinical Mouse Model of Radiation-Induced Heart Disease.
Kim K, Kim MM, Skoufos G, Diffenderfer ES, Motlagh SAO, Kokkorakis M, Koliaki I, Morcos G, Shoniyozov K, Griffin J, Hatzigeorgiou AG, Metz JM, Lin A, Feigenberg SJ, Cengel KA, Ky B, Koumenis C, Verginadis II. Kim K, et al. Among authors: verginadis ii. Int J Radiat Oncol Biol Phys. 2024 Jul 15;119(4):1234-1247. doi: 10.1016/j.ijrobp.2024.01.224. Epub 2024 Feb 15. Int J Radiat Oncol Biol Phys. 2024. PMID: 38364948 Free PMC article.
Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy.
Logotheti S, Pavlopoulou A, Rudsari HK, Galow AM, Kafalı Y, Kyrodimos E, Giotakis AI, Marquardt S, Velalopoulou A, Verginadis II, Koumenis C, Stiewe T, Zoidakis J, Balasingham I, David R, Georgakilas AG. Logotheti S, et al. Among authors: verginadis ii. Pharmacol Ther. 2024 Aug;260:108670. doi: 10.1016/j.pharmthera.2024.108670. Epub 2024 May 31. Pharmacol Ther. 2024. PMID: 38823489 Review.
Navigating the Critical Translational Questions for Implementing FLASH in the Clinic.
Loo BW Jr, Verginadis II, Sørensen BS, Mascia AE, Perentesis JP, Koong AC, Schüler E, Rankin EB, Maxim PG, Limoli CL, Vozenin MC. Loo BW Jr, et al. Among authors: verginadis ii. Semin Radiat Oncol. 2024 Jul;34(3):351-364. doi: 10.1016/j.semradonc.2024.04.008. Semin Radiat Oncol. 2024. PMID: 38880544 Review.
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis II, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, Minn AJ, Wrana JL, Lee CL, Kirsch DG. Morral C, et al. Among authors: verginadis ii. Nat Commun. 2024 Apr 8;15(1):3018. doi: 10.1038/s41467-024-47124-8. Nat Commun. 2024. PMID: 38589357 Free PMC article.
Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy.
Lim TL, Morral C, Verginadis II, Kim K, Luo L, Foley CJ, Kim MM, Li N, Yoshor B, Njah K, Putt M, Oliaei Motlagh SA, Velalopoulou A, Chowdhury P, Bicher S, Goia D, Lengner CJ, Wrana JL, Koumenis C, Minn AJ. Lim TL, et al. Among authors: verginadis ii. bioRxiv [Preprint]. 2024 Aug 19:2024.08.16.608284. doi: 10.1101/2024.08.16.608284. bioRxiv. 2024. PMID: 39229237 Free PMC article. Preprint.
Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.
Amit U, Uslu U, Verginadis II, Kim MM, Motlagh SAO, Diffenderfer ES, Assenmacher CA, Bicher S, Atoche SJ, Ben-Josef E, Young RM, June CH, Koumenis C. Amit U, et al. Among authors: verginadis ii. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2403002121. doi: 10.1073/pnas.2403002121. Epub 2024 Jul 24. Proc Natl Acad Sci U S A. 2024. PMID: 39047033 Free PMC article.
FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone.
Verginadis II, Velalopoulou A, Kim MM, Kim K, Paraskevaidis I, Bell B, Oliaei Motlagh SA, Karaj A, Banerjee E, Finesso G, Assenmacher CA, Radaelli E, Lu J, Lin Y, Putt ME, Diffenderfer ES, Guha C, Qin L, Metz JM, Maity A, Cengel KA, Koumenis C, Busch TM. Verginadis II, et al. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602528. doi: 10.1101/2024.07.08.602528. bioRxiv. 2024. PMID: 39026805 Free PMC article. Preprint.
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer.
Chowdhury P, Velalopoulou A, Verginadis II, Morcos G, Loo PE, Kim MM, Motlagh SAO, Shoniyozov K, Diffenderfer ES, Ocampo EA, Putt M, Assenmacher CA, Radaelli E, Lu J, Qin L, Liu H, Leli NM, Girdhani S, Denef N, Vander Stappen F, Cengel KA, Busch TM, Metz JM, Dong L, Lin A, Koumenis C. Chowdhury P, et al. Among authors: verginadis ii. Mol Cancer Ther. 2024 Jun 4;23(6):877-889. doi: 10.1158/1535-7163.MCT-23-0663. Mol Cancer Ther. 2024. PMID: 38593239 Free PMC article.
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities.
Lu Z, Bae EA, Verginadis II, Zhang H, Cho C, McBrearty N, George SS, Diehl JA, Koumenis C, Bradley LM, Fuchs SY. Lu Z, et al. Among authors: verginadis ii. Cancer Immunol Immunother. 2023 Apr;72(4):815-826. doi: 10.1007/s00262-022-03286-2. Epub 2022 Sep 5. Cancer Immunol Immunother. 2023. PMID: 36063172 Free PMC article.
43 results