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Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization.
Cerqua I, Musella S, Peltner LK, D'Avino D, Di Sarno V, Granato E, Vestuto V, Di Matteo R, Pace S, Ciaglia T, Bilancia R, Smaldone G, Di Matteo F, Di Micco S, Bifulco G, Pepe G, Basilicata MG, Rodriquez M, Gomez-Monterrey IM, Campiglia P, Ostacolo C, Roviezzo F, Werz O, Rossi A, Bertamino A. Cerqua I, et al. Among authors: roviezzo f. J Med Chem. 2022 Nov 10;65(21):14456-14480. doi: 10.1021/acs.jmedchem.2c00817. Epub 2022 Nov 1. J Med Chem. 2022. PMID: 36318728 Free PMC article.
Proteinase-activated receptor-2 mediates arterial vasodilation in diabetes.
Roviezzo F, Bucci M, Brancaleone V, Di Lorenzo A, Geppetti P, Farneti S, Parente L, Lungarella G, Fiorucci S, Cirino G. Roviezzo F, et al. Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2349-54. doi: 10.1161/01.ATV.0000184770.01494.2e. Epub 2005 Sep 1. Arterioscler Thromb Vasc Biol. 2005. PMID: 16141401
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.
Schaible AM, Filosa R, Temml V, Krauth V, Matteis M, Peduto A, Bruno F, Luderer S, Roviezzo F, Di Mola A, de Rosa M, D'Agostino B, Weinigel C, Barz D, Koeberle A, Pergola C, Schuster D, Werz O. Schaible AM, et al. Among authors: roviezzo f. Br J Pharmacol. 2014 May;171(9):2399-412. doi: 10.1111/bph.12592. Br J Pharmacol. 2014. PMID: 24467325 Free PMC article.
85 results