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Engineering the next generation of cell-based therapeutics.
Bashor CJ, Hilton IB, Bandukwala H, Smith DM, Veiseh O. Bashor CJ, et al. Nat Rev Drug Discov. 2022 Sep;21(9):655-675. doi: 10.1038/s41573-022-00476-6. Epub 2022 May 30. Nat Rev Drug Discov. 2022. PMID: 35637318 Free PMC article. Review.
Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control.
Mahata B, Cabrera A, Brenner DA, Guerra-Resendez RS, Li J, Goell J, Wang K, Guo Y, Escobar M, Parthasarathy AK, Szadowski H, Bedford G, Reed DR, Kim S, Hilton IB. Mahata B, et al. Among authors: hilton ib. Nat Methods. 2023 Nov;20(11):1716-1728. doi: 10.1038/s41592-023-02036-1. Epub 2023 Oct 9. Nat Methods. 2023. PMID: 37813990 Free PMC article.
Transgenic mice for in vivo epigenome editing with CRISPR-based systems.
Gemberling MP, Siklenka K, Rodriguez E, Tonn-Eisinger KR, Barrera A, Liu F, Kantor A, Li L, Cigliola V, Hazlett MF, Williams CA, Bartelt LC, Madigan VJ, Bodle JC, Daniels H, Rouse DC, Hilton IB, Asokan A, Ciofani M, Poss KD, Reddy TE, West AE, Gersbach CA. Gemberling MP, et al. Nat Methods. 2021 Aug;18(8):965-974. doi: 10.1038/s41592-021-01207-2. Epub 2021 Aug 2. Nat Methods. 2021. PMID: 34341582 Free PMC article.
Harnessing CRISPR-Cas9 for Epigenetic Engineering.
Guerra-Resendez RS, Hilton IB. Guerra-Resendez RS, et al. Methods Mol Biol. 2022;2518:237-251. doi: 10.1007/978-1-0716-2421-0_14. Methods Mol Biol. 2022. PMID: 35666449
46 results