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Page 1
Comorbidity between lung cancer and COVID-19 pneumonia: role of immunoregulatory gene transcripts in high ACE2-expressing normal lung.
Lazar V, Raynaud J, Magidi S, Bresson C, Martini JF, Galbraith S, Wunder F, Onn A, Batist G, Girard N, Lassen U, Pramesh CS, Al-Omari A, Ikeda S, Berchem G, Blay JY, Solomon B, Felip E, Tabernero J, Rubin E, Philip T, Porgador A, Berindan-Neagoe I, Schilsky RL, Kurzrock R. Lazar V, et al. Among authors: wunder f. Ther Adv Med Oncol. 2022 Oct 28;14:17588359221133893. doi: 10.1177/17588359221133893. eCollection 2022. Ther Adv Med Oncol. 2022. PMID: 36324736 Free PMC article.
Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial.
Rodon J, Soria JC, Berger R, Miller WH, Rubin E, Kugel A, Tsimberidou A, Saintigny P, Ackerstein A, Braña I, Loriot Y, Afshar M, Miller V, Wunder F, Bresson C, Martini JF, Raynaud J, Mendelsohn J, Batist G, Onn A, Tabernero J, Schilsky RL, Lazar V, Lee JJ, Kurzrock R. Rodon J, et al. Among authors: wunder f. Nat Med. 2019 May;25(5):751-758. doi: 10.1038/s41591-019-0424-4. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011205 Free PMC article. Clinical Trial.
Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival.
Lazar V, Magidi S, Girard N, Savignoni A, Martini JF, Massimini G, Bresson C, Berger R, Onn A, Raynaud J, Wunder F, Berindan-Neagoe I, Sekacheva M, Braña I, Tabernero J, Felip E, Porgador A, Kleinman C, Batist G, Solomon B, Tsimberidou AM, Soria JC, Rubin E, Kurzrock R, Schilsky RL. Lazar V, et al. Among authors: wunder f. NPJ Precis Oncol. 2021 Apr 28;5(1):33. doi: 10.1038/s41698-021-00171-6. NPJ Precis Oncol. 2021. PMID: 33911192 Free PMC article.
A WIN Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non-small cell lung cancer.
Solomon B, Callejo A, Bar J, Berchem G, Bazhenova L, Saintigny P, Wunder F, Raynaud J, Girard N, Lee JJ, Sulaiman R, Prouse B, Bresson C, Ventura H, Magidi S, Rubin E, Young B, Onn A, Leyland-Jones B, Schilsky RL, Lazar V, Felip E, Kurzrock R. Solomon B, et al. Among authors: wunder f. Cancer Med. 2022 Jul;11(14):2790-2800. doi: 10.1002/cam4.4635. Epub 2022 Mar 20. Cancer Med. 2022. PMID: 35307972 Free PMC article. Clinical Trial.
A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology.
Lazar V, Zhang B, Magidi S, Le Tourneau C, Raymond E, Ducreux M, Bresson C, Raynaud J, Wunder F, Onn A, Felip E, Tabernero J, Batist G, Kurzrock R, Rubin E, Schilsky RL. Lazar V, et al. Among authors: wunder f. Ther Adv Med Oncol. 2023 Mar 31;15:17588359231156382. doi: 10.1177/17588359231156382. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37025260 Free PMC article.
Identification of a central network hub of key prognostic genes based on correlation between transcriptomics and survival in patients with metastatic solid tumors.
Lazar V, Raymond E, Magidi S, Bresson C, Wunder F, Berindan-Neagoe I, Tijeras-Rabaland A, Raynaud J, Onn A, Ducreux M, Batist G, Lassen U, Cilius Nielsen F, Schilsky RL, Rubin E, Kurzrock R. Lazar V, et al. Among authors: wunder f. Ther Adv Med Oncol. 2024 Oct 17;16:17588359241289200. doi: 10.1177/17588359241289200. eCollection 2024. Ther Adv Med Oncol. 2024. PMID: 39429467 Free PMC article.
Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation.
Mauersberger C, Sager HB, Wobst J, Dang TA, Lambrecht L, Koplev S, Stroth M, Bettaga N, Schlossmann J, Wunder F, Friebe A, Björkegren JLM, Dietz L, Maas SL, van der Vorst EPC, Sandner P, Soehnlein O, Schunkert H, Kessler T. Mauersberger C, et al. Among authors: wunder f. Nat Cardiovasc Res. 2022 Dec;1(12):1174-1186. doi: 10.1038/s44161-022-00175-w. Epub 2022 Dec 12. Nat Cardiovasc Res. 2022. PMID: 37484062 Free PMC article.
Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY-747 designed for the treatment of resistant hypertension.
Wunder F, Stasch JP, Knorr A, Mondritzki T, Brockschnieder D, Becker-Pelster EM, Sandner P, Tinel H, Redlich G, Hartung IV, Vakalopoulos A, Follmann M. Wunder F, et al. Br J Pharmacol. 2023 Oct;180(19):2500-2513. doi: 10.1111/bph.16142. Epub 2023 Jun 20. Br J Pharmacol. 2023. PMID: 37170767 Free article.
New Generation of sGC Stimulators: Discovery of Imidazo[1,2-a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension.
Vakalopoulos A, Wunder F, Hartung IV, Redlich G, Jautelat R, Buchgraber P, Hassfeld J, Gromov AV, Lindner N, Bierer D, Gries J, Kroh W, Paulsen H, Mittendorf J, Lang D, Becker-Pelster E, Brockschnieder D, Geiss V, Li V, Straub A, Knorr A, Mondritzki T, Trübel H, Raschke M, Schaefer M, Thomas D, Sandner P, Stasch JP, Follmann M. Vakalopoulos A, et al. Among authors: wunder f. J Med Chem. 2023 Jun 8;66(11):7280-7303. doi: 10.1021/acs.jmedchem.2c02082. Epub 2023 Apr 11. J Med Chem. 2023. PMID: 37040336
BAY-6096: A Potent, Selective, and Highly Water-Soluble Adrenergic α2B Antagonist.
Meibom D, Meyer J, von Buehler CJ, Collins KD, Maassen S, Gericke KM, Hüser J, Mittendorf J, Ortega Hernandez N, Schamberger J, Stampfuss J, Straub A, Torge A, Witowski N, Wunder F. Meibom D, et al. Among authors: wunder f. J Med Chem. 2023 Apr 13;66(7):4659-4670. doi: 10.1021/acs.jmedchem.2c01690. Epub 2023 Mar 18. J Med Chem. 2023. PMID: 36932954 Free PMC article.
51 results