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Inhibition of the CCR6-CCL20 axis prevents regulatory T cell recruitment and sensitizes head and neck squamous cell carcinoma to radiation therapy.
Rutihinda C, Haroun R, Saidi NE, Ordoñez JP, Naasri S, Lévesque D, Boisvert FM, Fortier PH, Belzile M, Fradet L, Hubert-Tremblay V, Turgeon GA, Wang CS, Delage P, Rousseau É, Paquette B, Oweida AJ. Rutihinda C, et al. Among authors: oweida aj. Cancer Immunol Immunother. 2023 May;72(5):1089-1102. doi: 10.1007/s00262-022-03313-2. Epub 2022 Nov 3. Cancer Immunol Immunother. 2023. PMID: 36326893 Free PMC article.
Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide.
Oweida AJ, Mueller AC, Piper M, Milner D, Van Court B, Bhatia S, Phan A, Bickett T, Jordan K, Proia T, Schulick R, Messersmith WA, Del Chiaro M, Clambey E, Gough MJ, Williams J, Hansen K, Goodman K, Karam SD. Oweida AJ, et al. Cancer Immunol Immunother. 2021 Apr;70(4):989-1000. doi: 10.1007/s00262-020-02701-w. Epub 2020 Oct 23. Cancer Immunol Immunother. 2021. PMID: 33097963 Free PMC article.
Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis.
Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Knitz MW, et al. Among authors: oweida aj. J Immunother Cancer. 2021 Apr;9(4):e001955. doi: 10.1136/jitc-2020-001955. J Immunother Cancer. 2021. PMID: 33883256 Free PMC article.
PARP Inhibition Enhances Radiotherapy of SMAD4-Deficient Human Head and Neck Squamous Cell Carcinomas in Experimental Models.
Hernandez AL, Young CD, Bian L, Weigel K, Nolan K, Frederick B, Han G, He G, Devon Trahan G, Rudolph MC, Jones KL, Oweida AJ, Karam SD, Raben D, Wang XJ. Hernandez AL, et al. Among authors: oweida aj. Clin Cancer Res. 2020 Jun 15;26(12):3058-3070. doi: 10.1158/1078-0432.CCR-19-0514. Epub 2020 Mar 5. Clin Cancer Res. 2020. PMID: 32139402 Free PMC article.
Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.
Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Del Chiaro M, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Neto AG, Lagares D, Hansen KC, Van Bokhoven A, Karam SD. Mueller AC, et al. Among authors: oweida aj. Cancer Res. 2021 Jun 15;81(12):3255-3269. doi: 10.1158/0008-5472.CAN-20-3892. Epub 2021 Feb 1. Cancer Res. 2021. PMID: 33526513 Free PMC article.
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