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Chimeric mRNA-based COVID-19 vaccine induces protective immunity against Omicron and Delta variants.
Hu Q, Zhao Y, Shaabani N, Lyu X, Powers C, Sun H, Cruz V, Stegman K, Xu J, Fossier A, Huang Y, Ho G, Kao Y, Wang Z, Wang Z, Hu Y, Zheng Y, Kyaw L, Zuluaga C, Wang H, Pei H, Allen R, Xie H, Ji H, Chen R. Hu Q, et al. Among authors: chen r. Mol Ther Nucleic Acids. 2022 Dec 13;30:465-476. doi: 10.1016/j.omtn.2022.10.021. Epub 2022 Nov 2. Mol Ther Nucleic Acids. 2022. PMID: 36345542 Free PMC article.
Antibody-based binding domain fused to TCRγ chain facilitates T cell cytotoxicity for potent anti-tumor response.
Chen Z, Lin C, Pei H, Yuan X, Xu J, Zou M, Zhang X, Fossier A, Liu M, Goo S, Lei L, Yang J, Novick C, Xu J, Ying G, Zhou Z, Wu J, Tang C, Zhang W, Wang Z, Wang Z, Zhang H, Guo W, Hu Q, Ji H, Chen R. Chen Z, et al. Among authors: chen r. Oncogenesis. 2023 Jun 22;12(1):33. doi: 10.1038/s41389-023-00480-4. Oncogenesis. 2023. PMID: 37349298 Free PMC article.
Chronic viral mimicry induction following p53 loss promotes immune evasion.
Ishak CA, Marhon SA, Tchrakian N, Hodgson A, Loo Yau H, Gonzaga IM, Peralta M, Lungu IM, Gomez S, Liang SB, Shen SY, Chen R, Chen J, Chatterjee B, Wanniarachchi KN, Lee J, Zehrbach N, Hosseini A, Mehdipour P, Sun S, Solovyov A, Ettayebi I, Francis KE, He A, Wu T, Feng S, da Silva Medina T, Campos de Almeida F, Bayani J, Li J, MacDonald S, Wang Y, Garcia SS, Arthofer E, Diab N, Srivastava A, Austin PT, Sabatini PJB, Greenbaum BD, O'Brien CA, Shepherd TG, Tsao MS, Chiappinelli KB, Oza AM, Clarke BA, Rottapel R, Lheureux S, De Carvalho DD. Ishak CA, et al. Among authors: chen r. Cancer Discov. 2025 Jan 7. doi: 10.1158/2159-8290.CD-24-0094. Online ahead of print. Cancer Discov. 2025. PMID: 39776167
Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma.
Huang Y, He C, Hu Q, Liu Z, Li X, Gao W, Liang X, Chen R, Mao Z, Lin X. Huang Y, et al. Among authors: chen r. Invest Ophthalmol Vis Sci. 2025 Jan 2;66(1):11. doi: 10.1167/iovs.66.1.11. Invest Ophthalmol Vis Sci. 2025. PMID: 39775699
Genomic determinants of biological age estimated by deep learning applied to retinal images.
Huang Y, Syed MG, Chen R, Li C, Shang X, Wang W, Zhang X, Zhang X, Tang S, Liu J, Liu S, Srinivasan S, Hu Y, Mookiah MRK, Wang H, Trucco E, Yu H, Palmer C, Zhu Z, Doney ASF, He M. Huang Y, et al. Among authors: chen r. Geroscience. 2025 Jan 8. doi: 10.1007/s11357-024-01481-w. Online ahead of print. Geroscience. 2025. PMID: 39775603
Targeting Senescent Stemlike Subpopulations in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia.
Ding YY, Sussman JH, Madden K, Loftus JP, Chen RK, Falkenstein CD, Barcenas Lopez DA, Hottman DA, Mathier B, Yu W, Xu J, Chen C, Chen CH, He B, Bandyopadhyay S, Zhang Z, Lee D, Wang H, Peng J, Dang CV, Tan K, Tasian SK. Ding YY, et al. Among authors: chen rk. Blood. 2025 Jan 7:blood.2024026482. doi: 10.1182/blood.2024026482. Online ahead of print. Blood. 2025. PMID: 39774844
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