Brockmöller J - Search Results

1

Atypical Substrates of the Organic Cation Transporter 1.

Redeker KM, Jensen O, Gebauer L, Meyer-Tönnies MJ, Brockmöller J. Redeker KM, et al. Among authors: brockmoller j. Biomolecules. 2022 Nov 9;12(11):1664. doi: 10.3390/biom12111664. Biomolecules. 2022. PMID: 36359014 Free PMC article.

2

Stereoselectivity in the Membrane Transport of Phenylethylamine Derivatives by Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3.

Gebauer L, Rafehi M, Brockmöller J. Gebauer L, et al. Among authors: brockmoller j. Biomolecules. 2022 Oct 18;12(10):1507. doi: 10.3390/biom12101507. Biomolecules. 2022. PMID: 36291716 Free PMC article.

3

Combined and independent effects of OCT1 and CYP2D6 on the cellular disposition of drugs.

Gebauer L, Dücker C, Jensen O, Brockmöller J. Gebauer L, et al. Among authors: brockmoller j. Biomed Pharmacother. 2023 May;161:114454. doi: 10.1016/j.biopha.2023.114454. Epub 2023 Mar 3. Biomed Pharmacother. 2023. PMID: 36871537 Free article.

4

Stereoselective Inhibition of High- and Low-Affinity Organic Cation Transporters.

Gebauer L, Jensen O, Rafehi M, Brockmöller J. Gebauer L, et al. Among authors: brockmoller j. Mol Pharm. 2023 Dec 4;20(12):6289-6300. doi: 10.1021/acs.molpharmaceut.3c00691. Epub 2023 Nov 14. Mol Pharm. 2023. PMID: 37962560 Free PMC article.

5

Stereoselectivity in Cell Uptake by SLC22 Organic Cation Transporters 1, 2, and 3.

Gebauer L, Jensen O, Rafehi M, Brockmöller J. Gebauer L, et al. Among authors: brockmoller j. J Med Chem. 2023 Dec 14;66(23):15990-16001. doi: 10.1021/acs.jmedchem.3c01436. Epub 2023 Dec 5. J Med Chem. 2023. PMID: 38052451 Free PMC article.

6

Targeted mutagenesis of negatively charged amino acids outlining the substrate translocation path within the human organic cation transporter 3.

Redeker KM, Schröder S, Dücker C, Brockmöller J, Gebauer L. Redeker KM, et al. Among authors: brockmoller j. Biochem Pharmacol. 2024 May;223:116188. doi: 10.1016/j.bcp.2024.116188. Epub 2024 Apr 3. Biochem Pharmacol. 2024. PMID: 38580166 Free article.

7

Comprehensive characterization of the OCT1 phenylalanine-244-alanine substitution reveals highly substrate-dependent effects on transporter function.

Wittern CI, Schröder S, Jensen O, Brockmöller J, Gebauer L. Wittern CI, et al. Among authors: brockmoller j. J Biol Chem. 2024 Nov;300(11):107835. doi: 10.1016/j.jbc.2024.107835. Epub 2024 Sep 27. J Biol Chem. 2024. PMID: 39342994 Free PMC article.

8

An extended substrate spectrum of the proton organic cation antiporter and relation to other cation transporters.

Ali Khan C, Kirsch N, Brockmöller J, Redeker KM. Ali Khan C, et al. Among authors: brockmoller j. Basic Clin Pharmacol Toxicol. 2024 Dec;135(6):720-742. doi: 10.1111/bcpt.14090. Epub 2024 Oct 21. Basic Clin Pharmacol Toxicol. 2024. PMID: 39429132 Free PMC article.

9

Several orphan solute carriers functionally identified as organic cation transporters: Substrates specificity compared with known cation transporters.

Redeker KM, Brockmöller J. Redeker KM, et al. Among authors: brockmoller j. J Biol Chem. 2024 Sep;300(9):107629. doi: 10.1016/j.jbc.2024.107629. Epub 2024 Aug 3. J Biol Chem. 2024. PMID: 39098524 Free PMC article.

10

Intestinal Drug Absorption After Subarachnoid Hemorrhage and Elective Neurosurgery: Insights From Esomeprazole Pharmacokinetics.

Kranawetter B, Brockmöller J, Sindern J, Hapke A, Bruns E, Harnisch LO, Moerer O, Stenzig J, Mielke D, Rohde V, Abboud T. Kranawetter B, et al. Among authors: brockmoller j. Crit Care Med. 2025 Jan 1;53(1):e140-e150. doi: 10.1097/CCM.0000000000006512. Epub 2024 Nov 20. Crit Care Med. 2025. PMID: 39570079 Free PMC article.

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