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Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial.
Imamura K, Izumi Y, Nagai M, Nishiyama K, Watanabe Y, Hanajima R, Egawa N, Ayaki T, Oki R, Fujita K, Uozumi R, Morinaga A, Hirohashi T, Fujii Y, Yamamoto T, Tatebe H, Tokuda T, Takahashi N, Morita S, Takahashi R, Inoue H. Imamura K, et al. Among authors: takahashi n, takahashi r. EClinicalMedicine. 2022 Oct 25;53:101707. doi: 10.1016/j.eclinm.2022.101707. eCollection 2022 Nov. EClinicalMedicine. 2022. PMID: 36467452 Free PMC article.
Phosphorylation of α-synuclein at T64 results in distinct oligomers and exerts toxicity in models of Parkinson's disease.
Matsui H, Ito S, Matsui H, Ito J, Gabdulkhaev R, Hirose M, Yamanaka T, Koyama A, Kato T, Tanaka M, Uemura N, Matsui N, Hirokawa S, Yoshihama M, Shimozawa A, Kubo SI, Iwasaki K, Hasegawa M, Takahashi R, Hirai K, Kakita A, Onodera O. Matsui H, et al. Among authors: takahashi r. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2214652120. doi: 10.1073/pnas.2214652120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252975 Free PMC article.
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[No authors listed] [No authors listed] PMID: 38176797
3,114 results