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Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma.
Gwynne WD, Suk Y, Custers S, Mikolajewicz N, Chan JK, Zador Z, Chafe SC, Zhai K, Escudero L, Zhang C, Zaslaver O, Chokshi C, Shaikh MV, Bakhshinyan D, Burns I, Chaudhry I, Nachmani O, Mobilio D, Maich WT, Mero P, Brown KR, Quaile AT, Venugopal C, Moffat J, Montenegro-Burke JR, Singh SK. Gwynne WD, et al. Among authors: zhai k. Cancer Cell. 2022 Dec 12;40(12):1488-1502.e7. doi: 10.1016/j.ccell.2022.10.009. Epub 2022 Nov 10. Cancer Cell. 2022. PMID: 36368321 Free article.
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells.
Chokshi CR, Shaikh MV, Brakel B, Rossotti MA, Tieu D, Maich W, Anand A, Chafe SC, Zhai K, Suk Y, Kieliszek AM, Miletic P, Mikolajewicz N, Chen D, McNicol JD, Chan K, Tong AHY, Kuhlmann L, Liu L, Alizada Z, Mobilio D, Tatari N, Savage N, Aghaei N, Grewal S, Puri A, Subapanditha M, McKenna D, Ignatchenko V, Salamoun JM, Kwiecien JM, Wipf P, Sharlow ER, Provias JP, Lu JQ, Lazo JS, Kislinger T, Lu Y, Brown KR, Venugopal C, Henry KA, Moffat J, Singh SK. Chokshi CR, et al. Among authors: zhai k. Nat Med. 2024 Oct;30(10):2936-2946. doi: 10.1038/s41591-024-03138-9. Epub 2024 Aug 2. Nat Med. 2024. PMID: 39095594
De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases.
Kieliszek AM, Mobilio D, Bassey-Archibong BI, Johnson JW, Piotrowski ML, de Araujo ED, Sedighi A, Aghaei N, Escudero L, Ang P, Gwynne WD, Zhang C, Quaile A, McKenna D, Subapanditha M, Tokar T, Vaseem Shaikh M, Zhai K, Chafe SC, Gunning PT, Montenegro-Burke JR, Venugopal C, Magolan J, Singh SK. Kieliszek AM, et al. Among authors: zhai k. Cell Rep Med. 2024 Oct 15;5(10):101755. doi: 10.1016/j.xcrm.2024.101755. Epub 2024 Oct 4. Cell Rep Med. 2024. PMID: 39366383 Free PMC article.
366 results