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The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure.
Boyle LD, Miguelez-Crespo A, Paul M, Villalobos E, Toews JNC, Ivatt L, Nagy B, Magennis M, Homer NZM, Andrew R, Viau V, Hammond GL, Stimson RH, Walker BR, Nixon M. Boyle LD, et al. Among authors: nixon m. Nat Commun. 2025 Jan 9;16(1):545. doi: 10.1038/s41467-024-55693-x. Nat Commun. 2025. PMID: 39788946 Free PMC article.
Proof of concept for a superior therapeutic index of corticosterone compared with hydrocortisone in patients with congenital adrenal hyperplasia.
Kyle CJ, Boyle LD, Nixon M, Homer NZM, Simpson JP, Rutter A, Ramage LE, Kelman A, Freel EM, Andrew R, Walker BR, Stimson RH. Kyle CJ, et al. Among authors: nixon m. Eur J Endocrinol. 2024 Nov 27;191(6):535-544. doi: 10.1093/ejendo/lvae144. Eur J Endocrinol. 2024. PMID: 39546623 Free PMC article. Clinical Trial.
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
Bell RMB, Villalobos E, Nixon M, Miguelez-Crespo A, Murphy L, Fawkes A, Coutts A, Sharp MGF, Koerner MV, Allan E, Meijer OC, Houtman R, Odermatt A, Beck KR, Denham SG, Lee P, Homer NZM, Walker BR, Morgan RA. Bell RMB, et al. Among authors: nixon m. Mol Metab. 2021 Jun;48:101225. doi: 10.1016/j.molmet.2021.101225. Epub 2021 Mar 27. Mol Metab. 2021. PMID: 33785425 Free PMC article.
335 results