Larsson K - Search Results

1

Biosynthesis of prostaglandin 15dPGJ₂ -glutathione and 15dPGJ₂-cysteine conjugates in macrophages and mast cells via MGST3.

Steinmetz-Späh J, Liu J, Singh R, Ekoff M, Boddul S, Tang X, Bergqvist F, Idborg H, Heitel P, Rönnberg E, Merk D, Wermeling F, Haeggström JZ, Nilsson G, Steinhilber D, Larsson K, Korotkova M, Jakobsson PJ. Steinmetz-Späh J, et al. Among authors: larsson k. J Lipid Res. 2022 Dec;63(12):100310. doi: 10.1016/j.jlr.2022.100310. Epub 2022 Nov 9. J Lipid Res. 2022. PMID: 36370807 Free PMC article.

2

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.

Zirath H, Frenzel A, Oliynyk G, Segerström L, Westermark UK, Larsson K, Munksgaard Persson M, Hultenby K, Lehtiö J, Einvik C, Påhlman S, Kogner P, Jakobsson PJ, Henriksson MA. Zirath H, et al. Among authors: larsson k. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10258-63. doi: 10.1073/pnas.1222404110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733953 Free PMC article.

3

COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.

Larsson K, Kock A, Idborg H, Arsenian Henriksson M, Martinsson T, Johnsen JI, Korotkova M, Kogner P, Jakobsson PJ. Larsson K, et al. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8070-5. doi: 10.1073/pnas.1424355112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080408 Free PMC article.

4

Inhibition of microsomal prostaglandin E synthase-1 as targeted therapy in cancer treatment.

Larsson K, Jakobsson PJ. Larsson K, et al. Prostaglandins Other Lipid Mediat. 2015 Jul;120:161-5. doi: 10.1016/j.prostaglandins.2015.06.002. Epub 2015 Jun 20. Prostaglandins Other Lipid Mediat. 2015. PMID: 26100239 Review.

5

Deletion of mPGES-1 affects platelet functions in mice.

Raouf J, Mobarrez F, Larsson K, Jakobsson PJ, Korotkova M. Raouf J, et al. Among authors: larsson k. Clin Sci (Lond). 2016 Dec 1;130(24):2295-2303. doi: 10.1042/CS20160463. Epub 2016 Oct 7. Clin Sci (Lond). 2016. PMID: 27758933

6

Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth.

Kock A, Larsson K, Bergqvist F, Eissler N, Elfman LHM, Raouf J, Korotkova M, Johnsen JI, Jakobsson PJ, Kogner P. Kock A, et al. Among authors: larsson k. EBioMedicine. 2018 Jun;32:84-92. doi: 10.1016/j.ebiom.2018.05.008. Epub 2018 May 24. EBioMedicine. 2018. PMID: 29804818 Free PMC article.

7

Inhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells.

Bergqvist F, Ossipova E, Idborg H, Raouf J, Checa A, Englund K, Englund P, Khoonsari PE, Kultima K, Wheelock CE, Larsson K, Korotkova M, Jakobsson PJ. Bergqvist F, et al. Among authors: larsson k. Front Pharmacol. 2019 Jun 7;10:636. doi: 10.3389/fphar.2019.00636. eCollection 2019. Front Pharmacol. 2019. PMID: 31231223 Free PMC article.

8

Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone.

Larsson K, Steinmetz J, Bergqvist F, Arefin S, Spahiu L, Wannberg J, Pawelzik SC, Morgenstern R, Stenberg P, Kublickiene K, Korotkova M, Jakobsson PJ. Larsson K, et al. Br J Pharmacol. 2019 Dec;176(24):4625-4638. doi: 10.1111/bph.14827. Epub 2019 Dec 28. Br J Pharmacol. 2019. PMID: 31404942 Free PMC article.

9

Targeting the COX/mPGES-1/PGE₂ Pathway in Neuroblastoma.

Larsson K, Kock A, Kogner P, Jakobsson PJ. Larsson K, et al. Adv Exp Med Biol. 2019;1161:89-100. doi: 10.1007/978-3-030-21735-8_9. Adv Exp Med Biol. 2019. PMID: 31562624

10

Establishment of an in vitro 3D model for neuroblastoma enables preclinical investigation of combined tumor-stroma drug targeting.

Kock A, Bergqvist F, Steinmetz J, Elfman LHM, Korotkova M, Johnsen JI, Jakobsson PJ, Kogner P, Larsson K. Kock A, et al. Among authors: larsson k. FASEB J. 2020 Aug;34(8):11101-11114. doi: 10.1096/fj.202000684R. Epub 2020 Jul 5. FASEB J. 2020. PMID: 32623799

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