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Co-transducing B7H3 CAR-NK cells with the DNR preserves their cytolytic function against GBM in the presence of exogenous TGF-β.
Chaudhry K, Geiger A, Dowlati E, Lang H, Sohai DK, Hwang EI, Lazarski CA, Yvon E, Holdhoff M, Jones R, Savoldo B, Cruz CRY, Bollard CM. Chaudhry K, et al. Among authors: hwang ei. Mol Ther Methods Clin Dev. 2022 Oct 21;27:415-430. doi: 10.1016/j.omtm.2022.10.010. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36381305 Free PMC article.
A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.
Du X, Tang F, Liu M, Su J, Zhang Y, Wu W, Devenport M, Lazarski CA, Zhang P, Wang X, Ye P, Wang C, Hwang E, Zhu T, Xu T, Zheng P, Liu Y. Du X, et al. Cell Res. 2018 Apr;28(4):416-432. doi: 10.1038/s41422-018-0011-0. Epub 2018 Feb 22. Cell Res. 2018. PMID: 29472691 Free PMC article.
RNA aggregates harness the danger response for potent cancer immunotherapy.
Mendez-Gomez HR, DeVries A, Castillo P, von Roemeling C, Qdaisat S, Stover BD, Xie C, Weidert F, Zhao C, Moor R, Liu R, Soni D, Ogando-Rivas E, Chardon-Robles J, McGuiness J, Zhang D, Chung MC, Marconi C, Michel S, Barpujari A, Jobin GW, Thomas N, Ma X, Campaneria Y, Grippin A, Karachi A, Li D, Sahay B, Elliott L, Foster TP, Coleman KE, Milner RJ, Sawyer WG, Ligon JA, Simon E, Cleaver B, Wynne K, Hodik M, Molinaro AM, Guan J, Kellish P, Doty A, Lee JH, Massini T, Kresak JL, Huang J, Hwang EI, Kline C, Carrera-Justiz S, Rahman M, Gatica S, Mueller S, Prados M, Ghiaseddin AP, Silver NL, Mitchell DA, Sayour EJ. Mendez-Gomez HR, et al. Among authors: hwang ei. Cell. 2024 May 9;187(10):2521-2535.e21. doi: 10.1016/j.cell.2024.04.003. Epub 2024 May 1. Cell. 2024. PMID: 38697107
Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors.
Frederico SC, Raphael I, Nisnboym M, Huq S, Schlegel BT, Sneiderman CT, Jackson SA, Jain A, Olin MR, Rood BR, Pollack IF, Hwang EI, Rajasundaram D, Kohanbash G. Frederico SC, et al. Among authors: hwang ei. Expert Rev Clin Immunol. 2024 Nov;20(11):1411-1420. doi: 10.1080/1744666X.2024.2390023. Epub 2024 Aug 18. Expert Rev Clin Immunol. 2024. PMID: 39114885
Two clinically distinct cases of infant hemispheric glioma carrying ZCCHC8:ROS1 fusion and responding to entrectinib.
Papusha L, Zaytseva M, Panferova A, Druy A, Valiakhmetova A, Artemov A, Salnikova E, Kislyakov A, Imyanitov E, Karachunsky A, Maschan A, Hwang EI, Novichkova G, Packer RJ. Papusha L, et al. Among authors: hwang ei. Neuro Oncol. 2022 Jun 1;24(6):1029-1031. doi: 10.1093/neuonc/noac026. Neuro Oncol. 2022. PMID: 35196386 Free PMC article. No abstract available.
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