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Co-transducing B7H3 CAR-NK cells with the DNR preserves their cytolytic function against GBM in the presence of exogenous TGF-β.
Chaudhry K, Geiger A, Dowlati E, Lang H, Sohai DK, Hwang EI, Lazarski CA, Yvon E, Holdhoff M, Jones R, Savoldo B, Cruz CRY, Bollard CM. Chaudhry K, et al. Among authors: sohai dk. Mol Ther Methods Clin Dev. 2022 Oct 21;27:415-430. doi: 10.1016/j.omtm.2022.10.010. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36381305 Free PMC article.