Gregory KJ - Search Results

1

Publisher Correction to: Adenosine receptor signalling in Alzheimer's disease.

Trinh PNH, Baltos JA, Hellyer SD, May LT, Gregory KJ. Trinh PNH, et al. Among authors: gregory kj. Purinergic Signal. 2022 Dec;18(4):407. doi: 10.1007/s11302-022-09906-x. Purinergic Signal. 2022. PMID: 36383276 Free PMC article. No abstract available.

2

Quantification of adenosine A(1) receptor biased agonism: Implications for drug discovery.

Baltos JA, Gregory KJ, White PJ, Sexton PM, Christopoulos A, May LT. Baltos JA, et al. Among authors: gregory kj. Biochem Pharmacol. 2016 Jan 1;99:101-12. doi: 10.1016/j.bcp.2015.11.013. Epub 2015 Nov 12. Biochem Pharmacol. 2016. PMID: 26581123

3

Ligand-Independent Adenosine A2B Receptor Constitutive Activity as a Promoter of Prostate Cancer Cell Proliferation.

Vecchio EA, Tan CY, Gregory KJ, Christopoulos A, White PJ, May LT. Vecchio EA, et al. Among authors: gregory kj. J Pharmacol Exp Ther. 2016 Apr;357(1):36-44. doi: 10.1124/jpet.115.230003. Epub 2016 Jan 20. J Pharmacol Exp Ther. 2016. PMID: 26791603

4

Structure-Activity Analysis of Biased Agonism at the Human Adenosine A3 Receptor.

Baltos JA, Paoletta S, Nguyen AT, Gregory KJ, Tosh DK, Christopoulos A, Jacobson KA, May LT. Baltos JA, et al. Among authors: gregory kj. Mol Pharmacol. 2016 Jul;90(1):12-22. doi: 10.1124/mol.116.103283. Epub 2016 May 2. Mol Pharmacol. 2016. PMID: 27136943 Free PMC article.

5

Role of the Second Extracellular Loop of the Adenosine A1 Receptor on Allosteric Modulator Binding, Signaling, and Cooperativity.

Nguyen AT, Vecchio EA, Thomas T, Nguyen TD, Aurelio L, Scammells PJ, White PJ, Sexton PM, Gregory KJ, May LT, Christopoulos A. Nguyen AT, et al. Among authors: gregory kj. Mol Pharmacol. 2016 Dec;90(6):715-725. doi: 10.1124/mol.116.105015. Epub 2016 Sep 28. Mol Pharmacol. 2016. PMID: 27683013

6

Extracellular Loop 2 of the Adenosine A1 Receptor Has a Key Role in Orthosteric Ligand Affinity and Agonist Efficacy.

Nguyen AT, Baltos JA, Thomas T, Nguyen TD, Muñoz LL, Gregory KJ, White PJ, Sexton PM, Christopoulos A, May LT. Nguyen AT, et al. Among authors: gregory kj. Mol Pharmacol. 2016 Dec;90(6):703-714. doi: 10.1124/mol.116.105007. Epub 2016 Sep 28. Mol Pharmacol. 2016. PMID: 27683014

7

Neurobiological insights and novel therapeutic opportunities for CNS disorders from mGlu receptor allosteric and biased modulation.

Hellyer S, Leach K, Gregory KJ. Hellyer S, et al. Among authors: gregory kj. Curr Opin Pharmacol. 2017 Feb;32:49-55. doi: 10.1016/j.coph.2016.10.007. Epub 2016 Nov 11. Curr Opin Pharmacol. 2017. PMID: 27842256 Review.

8

"Selective" Class C G Protein-Coupled Receptor Modulators Are Neutral or Biased mGlu₅ Allosteric Ligands.

Hellyer SD, Albold S, Wang T, Chen ANY, May LT, Leach K, Gregory KJ. Hellyer SD, et al. Among authors: gregory kj. Mol Pharmacol. 2018 May;93(5):504-514. doi: 10.1124/mol.117.111518. Epub 2018 Mar 7. Mol Pharmacol. 2018. PMID: 29514854

9

Biased agonism and allosteric modulation of metabotropic glutamate receptor 5.

Trinh PNH, May LT, Leach K, Gregory KJ. Trinh PNH, et al. Among authors: gregory kj. Clin Sci (Lond). 2018 Nov 2;132(21):2323-2338. doi: 10.1042/CS20180374. Print 2018 Nov 15. Clin Sci (Lond). 2018. PMID: 30389826 Review.

10

Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology.

Sengmany K, Hellyer SD, Albold S, Wang T, Conn PJ, May LT, Christopoulos A, Leach K, Gregory KJ. Sengmany K, et al. Among authors: gregory kj. Neuropharmacology. 2019 May 1;149:83-96. doi: 10.1016/j.neuropharm.2019.02.005. Epub 2019 Feb 11. Neuropharmacology. 2019. PMID: 30763654 Free PMC article.

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