Chu Q - Search Results

1

Stearate-derived very long-chain fatty acids are indispensable to tumor growth.

Chu Q, Liu P, Song Y, Yang R, An J, Zhai X, Niu J, Yang C, Li B. Chu Q, et al. EMBO J. 2023 Jan 16;42(2):e111268. doi: 10.15252/embj.2022111268. Epub 2022 Nov 21. EMBO J. 2023. PMID: 36408830 Free PMC article.

2

Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia.

Wang Y, Bai C, Ruan Y, Liu M, Chu Q, Qiu L, Yang C, Li B. Wang Y, et al. Among authors: chu q. Nat Commun. 2019 Jan 14;10(1):201. doi: 10.1038/s41467-018-08033-9. Nat Commun. 2019. PMID: 30643150 Free PMC article.

3

Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.

Liu M, Wang Y, Yang C, Ruan Y, Bai C, Chu Q, Cui Y, Chen C, Ying G, Li B. Liu M, et al. Among authors: chu q. J Exp Med. 2020 Mar 2;217(3):e20191226. doi: 10.1084/jem.20191226. J Exp Med. 2020. PMID: 31961917 Free PMC article.

4

SY-707, an ALK/FAK/IGF1R inhibitor, suppresses growth and metastasis of breast cancer cells.

Liu P, Sun Y, Liu S, Niu J, Liu X, Chu Q. Liu P, et al. Among authors: chu q. Acta Biochim Biophys Sin (Shanghai). 2022 Feb 25;54(2):252-260. doi: 10.3724/abbs.2022008. Acta Biochim Biophys Sin (Shanghai). 2022. PMID: 35538024 Free PMC article.

5

Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.

Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B. Yang R, et al. Among authors: chu q. Nat Commun. 2022 Nov 17;13(1):7031. doi: 10.1038/s41467-022-34850-0. Nat Commun. 2022. PMID: 36396642 Free PMC article.

6

Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.

Chu Q, An J, Liu P, Song Y, Zhai X, Yang R, Niu J, Yang C, Li B. Chu Q, et al. J Exp Med. 2023 Mar 6;220(3):e20221316. doi: 10.1084/jem.20221316. Epub 2022 Dec 15. J Exp Med. 2023. PMID: 36520461 Free PMC article.

7

De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.

Yang C, Zhao Y, Wang L, Guo Z, Ma L, Yang R, Wu Y, Li X, Niu J, Chu Q, Fu Y, Li B. Yang C, et al. Among authors: chu q. Nat Cell Biol. 2023 Jun;25(6):836-847. doi: 10.1038/s41556-023-01146-4. Epub 2023 Jun 8. Nat Cell Biol. 2023. PMID: 37291265

8

Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle.

Guo Z, Zhang Y, Wang H, Liao L, Ma L, Zhao Y, Yang R, Li X, Niu J, Chu Q, Fu Y, Li B, Yang C. Guo Z, et al. Among authors: chu q. Nat Commun. 2024 Aug 12;15(1):6915. doi: 10.1038/s41467-024-51232-w. Nat Commun. 2024. PMID: 39134530 Free PMC article.

9

AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress.

Zhai X, Yang R, Chu Q, Guo Z, Hou P, Li X, Bai C, Lu Z, Qiao L, Fu Y, Niu J, Li B. Zhai X, et al. Among authors: chu q. Nat Cell Biol. 2025 Jan 2. doi: 10.1038/s41556-024-01549-x. Online ahead of print. Nat Cell Biol. 2025. PMID: 39747579

10

CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.

Chu Q, Wang L, Zhang J, Wang W, Wang Y. Chu Q, et al. Cancer Med. 2021 Jun;10(11):3689-3699. doi: 10.1002/cam4.3916. Epub 2021 May 7. Cancer Med. 2021. PMID: 33960694 Free PMC article.

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