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Page 1
iPSC-Derived Neurons from Patients with POLG Mutations Exhibit Decreased Mitochondrial Content and Dendrite Simplification.
Verma M, Francis L, Lizama BN, Callio J, Fricklas G, Wang KZQ, Kaufman BA, D'Aiuto L, Stolz DB, Watkins SC, Nimgaonkar VL, Soto-Gutierrez A, Goldstein A, Chu CT. Verma M, et al. Among authors: stolz db. Am J Pathol. 2023 Feb;193(2):201-212. doi: 10.1016/j.ajpath.2022.11.002. Epub 2022 Nov 19. Am J Pathol. 2023. PMID: 36414085 Free PMC article.
Insulin secretion deficits in a Prader-Willi syndrome β-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones.
Koppes EA, Johnson MA, Moresco JJ, Luppi P, Lewis DW, Stolz DB, Diedrich JK, Yates JR 3rd, Wek RC, Watkins SC, Gollin SM, Park HJ, Drain P, Nicholls RD. Koppes EA, et al. Among authors: stolz db. PLoS Genet. 2023 Apr 17;19(4):e1010710. doi: 10.1371/journal.pgen.1010710. eCollection 2023 Apr. PLoS Genet. 2023. PMID: 37068109 Free PMC article.
Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types.
Maggiore JC, LeGraw R, Przepiorski A, Velazquez J, Chaney C, Streeter E, Silva-Barbosa A, Franks J, Hislop J, Hill A, Wu H, Pfister K, Howden SE, Watkins SC, Little M, Humphreys BD, Watson A, Stolz DB, Kiani S, Davidson AJ, Carroll TJ, Cleaver O, Sims-Lucas S, Ebrahimkhani MR, Hukriede NA. Maggiore JC, et al. Among authors: stolz db. bioRxiv [Preprint]. 2023 May 30:2023.05.30.542848. doi: 10.1101/2023.05.30.542848. bioRxiv. 2023. Update in: Kidney Int. 2024 Dec;106(6):1086-1100. doi: 10.1016/j.kint.2024.05.026 PMID: 37333155 Free PMC article. Updated. Preprint.
A genetically inducible endothelial niche enables vascularization of human kidney organoids with multilineage maturation and emergence of renin expressing cells.
Maggiore JC, LeGraw R, Przepiorski A, Velazquez J, Chaney C, Vanichapol T, Streeter E, Almuallim Z, Oda A, Chiba T, Silva-Barbosa A, Franks J, Hislop J, Hill A, Wu H, Pfister K, Howden SE, Watkins SC, Little MH, Humphreys BD, Kiani S, Watson A, Stolz DB, Davidson AJ, Carroll T, Cleaver O, Sims-Lucas S, Ebrahimkhani MR, Hukriede NA. Maggiore JC, et al. Among authors: stolz db. Kidney Int. 2024 Dec;106(6):1086-1100. doi: 10.1016/j.kint.2024.05.026. Epub 2024 Jun 18. Kidney Int. 2024. PMID: 38901605 Free article.
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Stolz DB, Wallace CT, Yu-Wei C, Franks J, Bose D, Shang P, Ambrosino HM, Dutton JR, Geng Z, Montford J, Ryu J, Rajasundaram D, Hose S, Sahel JA, Puertollano R, Finkel T, Zigler JS Jr, Sergeev Y, Watkins SC, Goetzman ES, Ferrington DA, Flores-Bellver M, Kaarniranta K, Sodhi A, Bharti K, Handa JT, Sinha D. Ghosh S, et al. Among authors: stolz db. Nat Commun. 2024 Jul 21;15(1):6150. doi: 10.1038/s41467-024-50500-z. Nat Commun. 2024. PMID: 39034314 Free PMC article.
Human-induced pluripotent stem cell-based hepatic modeling of lipid metabolism-associated TM6SF2-E167K variant.
Faccioli LAP, Sun Y, Animasahun O, Motomura T, Liu Z, Kurihara T, Hu Z, Yang B, Cetin Z, Baratta AM, Shankaran A, Nenwani M, Altay LN, Huang L, Meurs N, Franks J, Stolz D, Gavlock DC, Miedel MT, Ostrowska A, Florentino RM, Fox IJ, Nagrath D, Soto-Gutierrez A. Faccioli LAP, et al. Hepatology. 2024 Aug 27. doi: 10.1097/HEP.0000000000001065. Online ahead of print. Hepatology. 2024. PMID: 39190693
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y. Klimas A, et al. Among authors: stolz db. Nat Biotechnol. 2023 Jun;41(6):858-869. doi: 10.1038/s41587-022-01546-1. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593399 Free PMC article.
Modelling Human Post-Implantation Development via Extra-Embryonic Niche Engineering.
Hislop J, Alavi A, Song Q, Schoenberger R, Kamyar KF, LeGraw R, Velazquez J, Mokhtari T, Taheri MN, Rytel M, de Sousa Lopes SMC, Watkins S, Stolz D, Kiani S, Sozen B, Bar-Joseph Z, Ebrahimkhani MR. Hislop J, et al. bioRxiv [Preprint]. 2023 Jul 24:2023.06.15.545118. doi: 10.1101/2023.06.15.545118. bioRxiv. 2023. Update in: Nature. 2024 Feb;626(7998):367-376. doi: 10.1038/s41586-023-06914-8 PMID: 37398391 Free PMC article. Updated. Preprint.
Modelling post-implantation human development to yolk sac blood emergence.
Hislop J, Song Q, Keshavarz F K, Alavi A, Schoenberger R, LeGraw R, Velazquez JJ, Mokhtari T, Taheri MN, Rytel M, Chuva de Sousa Lopes SM, Watkins S, Stolz D, Kiani S, Sozen B, Bar-Joseph Z, Ebrahimkhani MR. Hislop J, et al. Nature. 2024 Feb;626(7998):367-376. doi: 10.1038/s41586-023-06914-8. Epub 2023 Dec 13. Nature. 2024. PMID: 38092041 Free PMC article.
368 results