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Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis.
Heath J, Chour W, Choi J, Xie J, Chaffee M, Schmitt T, Finton K, Delucia D, Xu A, Su Y, Chen D, Zhang R, Yuan D, Hong S, Ng A, Butler J, Edmark R, Jones L, Murray K, Peng S, Li G, Strong R, Lee J, Goldman J, Greenberg P. Heath J, et al. Among authors: su y. Res Sq [Preprint]. 2022 Nov 18:rs.3.rs-1090664. doi: 10.21203/rs.3.rs-1090664/v1. Res Sq. 2022. Update in: Commun Biol. 2023 May 16;6(1):528. doi: 10.1038/s42003-023-04899-8 PMID: 36415462 Free PMC article. Updated. Preprint.
A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication.
Zhou J, Bethune MT, Malkova N, Sutherland AM, Comin-Anduix B, Su Y, Baltimore D, Ribas A, Heath JR. Zhou J, et al. Among authors: su y. PLoS One. 2018 Jan 23;13(1):e0191634. doi: 10.1371/journal.pone.0191634. eCollection 2018. PLoS One. 2018. PMID: 29360859 Free PMC article.
T cell antigen discovery via trogocytosis.
Li G, Bethune MT, Wong S, Joglekar AV, Leonard MT, Wang JK, Kim JT, Cheng D, Peng S, Zaretsky JM, Su Y, Luo Y, Heath JR, Ribas A, Witte ON, Baltimore D. Li G, et al. Among authors: su y. Nat Methods. 2019 Feb;16(2):183-190. doi: 10.1038/s41592-018-0305-7. Epub 2019 Jan 28. Nat Methods. 2019. PMID: 30700903 Free PMC article.
Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.
Peng S, Zaretsky JM, Ng AHC, Chour W, Bethune MT, Choi J, Hsu A, Holman E, Ding X, Guo K, Kim J, Xu AM, Heath JE, Noh WJ, Zhou J, Su Y, Lu Y, McLaughlin J, Cheng D, Witte ON, Baltimore D, Ribas A, Heath JR. Peng S, et al. Among authors: su y. Cell Rep. 2019 Sep 3;28(10):2728-2738.e7. doi: 10.1016/j.celrep.2019.07.106. Cell Rep. 2019. PMID: 31484081 Free PMC article.
Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.
Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, Xu A, Li J, Dong S, Rothchild A, Zhou J, Murray K, Edmark R, Hong S, Jones L, Zhou Y, Roper R, Mackay S, O'Mahony DS, Dale CR, Wallick JA, Algren HA, Michael ZA, Magis A, Wei W, Price ND, Huang S, Subramanian N, Wang K, Hadlock J, Hood L, Aderem A, Bluestone JA, Lanier LL, Greenberg P, Gottardo R, Davis MM, Goldman JD, Heath JR. Su Y, et al. bioRxiv [Preprint]. 2020 Jul 31:2020.07.27.224063. doi: 10.1101/2020.07.27.224063. bioRxiv. 2020. PMID: 32766585 Free PMC article. Preprint.
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