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Page 1
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Piel S, Janowska JI, Ward JL, McManus MJ, Jose JS, Starr J, Sheldon M, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Piel S, et al. Among authors: mcmanus mj. Sci Rep. 2022 Nov 25;12(1):20329. doi: 10.1038/s41598-022-24472-3. Sci Rep. 2022. PMID: 36434021 Free PMC article.
Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat.
Piel S, Janowska JI, Ward JL, McManus MJ, Aronowitz DI, Janowski PK, Starr J, Hook JN, Hefti MM, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Piel S, et al. Among authors: mcmanus mj. Mol Cell Biochem. 2023 Jun;478(6):1231-1244. doi: 10.1007/s11010-022-04589-9. Epub 2022 Oct 25. Mol Cell Biochem. 2023. PMID: 36282352 Free PMC article.
Effect of dimethyl fumarate on mitochondrial metabolism in a pediatric porcine model of asphyxia-induced in-hospital cardiac arrest.
Piel S, McManus MJ, Heye KN, Beaulieu F, Fazelinia H, Janowska JI, MacTurk B, Starr J, Gaudio H, Patel N, Hefti MM, Smalley ME, Hook JN, Kohli NV, Bruton J, Hallowell T, Delso N, Roberts A, Lin Y, Ehinger JK, Karlsson M, Berg RA, Morgan RW, Kilbaugh TJ. Piel S, et al. Among authors: mcmanus mj. Sci Rep. 2024 Jun 15;14(1):13852. doi: 10.1038/s41598-024-64317-9. Sci Rep. 2024. PMID: 38879681 Free PMC article.
Mitochondrial antioxidants abate SARS-COV-2 pathology in mice.
Guarnieri JW, Lie T, Albrecht YES, Hewin P, Jurado KA, Widjaja GA, Zhu Y, McManus MJ, Kilbaugh TJ, Keith K, Potluri P, Taylor D, Angelin A, Murdock DG, Wallace DC. Guarnieri JW, et al. Among authors: mcmanus mj. Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2321972121. doi: 10.1073/pnas.2321972121. Epub 2024 Jul 15. Proc Natl Acad Sci U S A. 2024. PMID: 39008677 Free PMC article.
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. Sturm G, et al. Among authors: mcmanus mj. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. Commun Biol. 2023. PMID: 36635485 Free PMC article.
54 results