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Only FLT3-ITD co-mutation did not have a deleterious effect on acute myeloid leukemia patients with NPM1 mutation, but concomitant with DNMT3A co-mutation or a < 3log reduction of MRD2 predicted poor survival.
Duan W, Jia J, Wang J, Liu X, Yu W, Zhu X, Zhao T, Jiang Q, Ruan G, Zhao X, Shi H, Chang Y, Wang Y, Xu L, Zhang X, Huang X, Jiang H. Duan W, et al. Among authors: wang j, wang y. Ann Hematol. 2024 Nov;103(11):4525-4535. doi: 10.1007/s00277-024-06001-6. Epub 2024 Sep 17. Ann Hematol. 2024. PMID: 39287653
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