Shumar SA - Search Results

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NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet.

Vickers SD, Shumar SA, Saporito DC, Kunovac A, Hathaway QA, Mintmier B, King JA, King RD, Rajendran VM, Infante AM, Hollander JM, Leonardi R. Vickers SD, et al. Among authors: shumar sa. J Biol Chem. 2023 Jan;299(1):102745. doi: 10.1016/j.jbc.2022.102745. Epub 2022 Nov 24. J Biol Chem. 2023. PMID: 36436558 Free PMC article.

Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform.

Shumar SA, Kerr EW, Geldenhuys WJ, Montgomery GE, Fagone P, Thirawatananond P, Saavedra H, Gabelli SB, Leonardi R. Shumar SA, et al. J Biol Chem. 2018 Mar 16;293(11):4134-4148. doi: 10.1074/jbc.RA117.001358. Epub 2018 Jan 29. J Biol Chem. 2018. PMID: 29378847 Free PMC article.

Overexpression of Nudt7 decreases bile acid levels and peroxisomal fatty acid oxidation in the liver.

Shumar SA, Kerr EW, Fagone P, Infante AM, Leonardi R. Shumar SA, et al. J Lipid Res. 2019 May;60(5):1005-1019. doi: 10.1194/jlr.M092676. Epub 2019 Mar 7. J Lipid Res. 2019. PMID: 30846528 Free PMC article.

Nudt8 is a novel CoA diphosphohydrolase that resides in the mitochondria.

Kerr EW, Shumar SA, Leonardi R. Kerr EW, et al. Among authors: shumar sa. FEBS Lett. 2019 Jun;593(11):1133-1143. doi: 10.1002/1873-3468.13392. Epub 2019 May 2. FEBS Lett. 2019. PMID: 31004344 Free PMC article.

[No title available]

[No authors listed] [No authors listed] PMID: 33487369

Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice.

Shumar SA, Fagone P, Alfonso-Pecchio A, Gray JT, Rehg JE, Jackowski S, Leonardi R. Shumar SA, et al. PLoS One. 2015 Jun 8;10(6):e0130013. doi: 10.1371/journal.pone.0130013. eCollection 2015. PLoS One. 2015. PMID: 26052948 Free PMC article.

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