Desnoyer R - Search Results

1

Distinct Mechanisms of β-Arrestin-Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality.

Jara ZP, Harford TJ, Singh KD, Desnoyer R, Kumar A, Srinivasan D, Karnik SS. Jara ZP, et al. Among authors: desnoyer r. Hypertension. 2023 Feb;80(2):385-402. doi: 10.1161/HYPERTENSIONAHA.122.19232. Epub 2022 Nov 28. Hypertension. 2023. PMID: 36440576 Free PMC article.

2

Divergent Spatiotemporal Interaction of Angiotensin Receptor Blocking Drugs with Angiotensin Type 1 Receptor.

Singh KD, Unal H, Desnoyer R, Karnik SS. Singh KD, et al. Among authors: desnoyer r. J Chem Inf Model. 2018 Jan 22;58(1):182-193. doi: 10.1021/acs.jcim.7b00424. Epub 2017 Dec 27. J Chem Inf Model. 2018. PMID: 29195045 Free PMC article.

3

Mechanism of Hormone Peptide Activation of a GPCR: Angiotensin II Activated State of AT₁R Initiated by van der Waals Attraction.

Singh KD, Unal H, Desnoyer R, Karnik SS. Singh KD, et al. Among authors: desnoyer r. J Chem Inf Model. 2019 Jan 28;59(1):373-385. doi: 10.1021/acs.jcim.8b00583. Epub 2019 Jan 16. J Chem Inf Model. 2019. PMID: 30608150 Free PMC article.

4

Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers.

Singh KD, Jara ZP, Harford T, Saha PP, Pardhi TR, Desnoyer R, Karnik SS. Singh KD, et al. Among authors: desnoyer r. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2019126118. doi: 10.1073/pnas.2019126118. Proc Natl Acad Sci U S A. 2021. PMID: 34380734 Free PMC article.

5

Role of nuclear unphosphorylated STAT3 in angiotensin II type 1 receptor-induced cardiac hypertrophy.

Yue H, Li W, Desnoyer R, Karnik SS. Yue H, et al. Among authors: desnoyer r. Cardiovasc Res. 2010 Jan 1;85(1):90-9. doi: 10.1093/cvr/cvp285. Cardiovasc Res. 2010. PMID: 19696070 Free PMC article.

6

Effect of novel GPCR ligands on blood pressure and vascular homeostasis.

Jara ZP, Singh KD, Unal H, Desnoyer R, Yokota R, Pesquero JL, Casarini DE, Karnik SS. Jara ZP, et al. Among authors: desnoyer r. Methods Cell Biol. 2019;149:215-238. doi: 10.1016/bs.mcb.2018.10.001. Epub 2018 Nov 20. Methods Cell Biol. 2019. PMID: 30616822 Free PMC article.

7

Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts.

Chatterjee A, Barnard J, Moravec C, Desnoyer R, Tirupula K, Karnik SS. Chatterjee A, et al. Among authors: desnoyer r. PLoS One. 2017 Dec 29;12(12):e0190217. doi: 10.1371/journal.pone.0190217. eCollection 2017. PLoS One. 2017. PMID: 29287092 Free PMC article.

8

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor.

Zhang H, Unal H, Desnoyer R, Han GW, Patel N, Katritch V, Karnik SS, Cherezov V, Stevens RC. Zhang H, et al. Among authors: desnoyer r. J Biol Chem. 2015 Dec 4;290(49):29127-39. doi: 10.1074/jbc.M115.689000. Epub 2015 Sep 29. J Biol Chem. 2015. PMID: 26420482 Free PMC article.

9

Site-specific cleavage of G protein-coupled receptor-engaged beta-arrestin. Influence of the AT1 receptor conformation on scissile site selection.

Lee C, Bhatt S, Shukla A, Desnoyer RW, Yadav SP, Kim M, Jang SH, Karnik SS. Lee C, et al. J Biol Chem. 2008 Aug 1;283(31):21612-20. doi: 10.1074/jbc.M803062200. Epub 2008 May 27. J Biol Chem. 2008. PMID: 18505723 Free PMC article.

10

Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor.

Unal H, Jagannathan R, Bhatnagar A, Tirupula K, Desnoyer R, Karnik SS. Unal H, et al. Among authors: desnoyer r. J Biol Chem. 2013 Jan 4;288(1):540-51. doi: 10.1074/jbc.M112.392514. Epub 2012 Nov 8. J Biol Chem. 2013. PMID: 23139413 Free PMC article.

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