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Page 1
Trial of Deferiprone in Parkinson's Disease.
Devos D, Labreuche J, Rascol O, Corvol JC, Duhamel A, Guyon Delannoy P, Poewe W, Compta Y, Pavese N, Růžička E, Dušek P, Post B, Bloem BR, Berg D, Maetzler W, Otto M, Habert MO, Lehericy S, Ferreira J, Dodel R, Tranchant C, Eusebio A, Thobois S, Marques AR, Meissner WG, Ory-Magne F, Walter U, de Bie RMA, Gago M, Vilas D, Kulisevsky J, Januario C, Coelho MVS, Behnke S, Worth P, Seppi K, Ouk T, Potey C, Leclercq C, Viard R, Kuchcinski G, Lopes R, Pruvo JP, Pigny P, Garçon G, Simonin O, Carpentier J, Rolland AS, Nyholm D, Scherfler C, Mangin JF, Chupin M, Bordet R, Dexter DT, Fradette C, Spino M, Tricta F, Ayton S, Bush AI, Devedjian JC, Duce JA, Cabantchik I, Defebvre L, Deplanque D, Moreau C; FAIRPARK-II Study Group. Devos D, et al. Among authors: bush ai. N Engl J Med. 2022 Dec 1;387(22):2045-2055. doi: 10.1056/NEJMoa2209254. N Engl J Med. 2022. PMID: 36449420 Clinical Trial.
How iron can drive neurodegeneration.
Kenkhuis B, Bush AI, Ayton S. Kenkhuis B, et al. Among authors: bush ai. Trends Neurosci. 2023 May;46(5):333-335. doi: 10.1016/j.tins.2023.02.003. Epub 2023 Feb 24. Trends Neurosci. 2023. PMID: 36842947
Vitamin A metabolites inhibit ferroptosis.
Jakaria M, Belaidi AA, Bush AI, Ayton S. Jakaria M, et al. Among authors: bush ai. Biomed Pharmacother. 2023 Aug;164:114930. doi: 10.1016/j.biopha.2023.114930. Epub 2023 May 24. Biomed Pharmacother. 2023. PMID: 37236031 Free article.
Small extracellular vesicles contain metals and transfer metal intercellularly.
Purnianto A, Mawal C, Kulkarni MM, Su H, Koukoulis TF, Wongsodirdjo P, Hung YH, Ayton S, Bush AI, Barnham KJ, Vella LJ. Purnianto A, et al. Among authors: bush ai. J Extracell Biol. 2024 Oct 14;3(10):e70012. doi: 10.1002/jex2.70012. eCollection 2024 Oct. J Extracell Biol. 2024. PMID: 39403171 Free PMC article.
Clinical quantitative susceptibility mapping (QSM): Biometal imaging and its emerging roles in patient care.
Wang Y, Spincemaille P, Liu Z, Dimov A, Deh K, Li J, Zhang Y, Yao Y, Gillen KM, Wilman AH, Gupta A, Tsiouris AJ, Kovanlikaya I, Chiang GC, Weinsaft JW, Tanenbaum L, Chen W, Zhu W, Chang S, Lou M, Kopell BH, Kaplitt MG, Devos D, Hirai T, Huang X, Korogi Y, Shtilbans A, Jahng GH, Pelletier D, Gauthier SA, Pitt D, Bush AI, Brittenham GM, Prince MR. Wang Y, et al. Among authors: bush ai. J Magn Reson Imaging. 2017 Oct;46(4):951-971. doi: 10.1002/jmri.25693. Epub 2017 Mar 10. J Magn Reson Imaging. 2017. PMID: 28295954 Free PMC article. Review.
Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis.
Hilton JBW, Kysenius K, Liddell JR, Mercer SW, Rautengarten C, Hare DJ, Buncic G, Paul B, Murray SS, McLean CA, Kilpatrick TJ, Beckman JS, Ayton S, Bush AI, White AR, Roberts BR, Donnelly PS, Crouch PJ. Hilton JBW, et al. Among authors: bush ai. Neurotherapeutics. 2024 Sep;21(5):e00432. doi: 10.1016/j.neurot.2024.e00432. Epub 2024 Aug 19. Neurotherapeutics. 2024. PMID: 39164165 Free PMC article.
Microglial ferroptotic stress causes non-cell autonomous neuronal death.
Liddell JR, Hilton JBW, Kysenius K, Billings JL, Nikseresht S, McInnes LE, Hare DJ, Paul B, Mercer SW, Belaidi AA, Ayton S, Roberts BR, Beckman JS, McLean CA, White AR, Donnelly PS, Bush AI, Crouch PJ. Liddell JR, et al. Among authors: bush ai. Mol Neurodegener. 2024 Feb 5;19(1):14. doi: 10.1186/s13024-023-00691-8. Mol Neurodegener. 2024. PMID: 38317225 Free PMC article.
In defence of ferroptosis.
Alves F, Lane D, Nguyen TPM, Bush AI, Ayton S. Alves F, et al. Among authors: bush ai. Signal Transduct Target Ther. 2025 Jan 3;10(1):2. doi: 10.1038/s41392-024-02088-5. Signal Transduct Target Ther. 2025. PMID: 39746918 Free PMC article. Review.
Deferiprone in Alzheimer Disease: A Randomized Clinical Trial.
Ayton S, Barton D, Brew B, Brodtmann A, Clarnette R, Desmond P, Devos D, Ellis KA, Fazlollahi A, Fradette C, Goh AMY, Kalinowski P, Kyndt C, Lai R, Lim YY, Maruff P, O'Brien TJ, Rowe C, Salvado O, Schofield PW, Spino M, Tricta F, Wagen A, Williams R, Woodward M, Bush AI. Ayton S, et al. Among authors: bush ai. JAMA Neurol. 2024 Nov 4:e243733. doi: 10.1001/jamaneurol.2024.3733. Online ahead of print. JAMA Neurol. 2024. PMID: 39495531
496 results